In biomass gasification, efficiency of energy quantification is a difficult part without finishing the process. In this article, a radial basis function neural network (RBFN) is proposed to predict biomass efficiency before gasification. RBFN will be compared with a principal component regression (PCR) and a multilayer perceptron neural network (MLPN). Due to the high dimensionality of data, principal component transform is first used in PCR and afterwards, ordinary regression is applied to selected principal components for modeling. Multilayer perceptron neural network (MLPN) is also used without any preprocessing. For this research, 3 wood samples and 3 other feedstock are used and they are near infrared (NIR) spectrum data with high-dimensionality. Ash and char are used as response variables. The comparison results of two responses will be shown.