Motion-compensated frame interpolation (MCFI) techniques in video signal processing have many application areas. Frame rate up-conversion (FRUC) or distributed video coding (DVC) technique needs an effective MCFI algorithm. For these applications, it is necessary to develop an effective post-processing technique to improve visual qualities or to reduce virtual channel noises, resulting in the reduced channel bit rate. This paper proposes a reliability evaluation method based on spatio-temporal characteristics for motion-compensated interpolated blocks. The proposed algorithm investigates the temporal matching characteristics for current frame and then is designed in such a way that it can measure temporal characteristics as well as the spatial ones. Through computer simulations, it is shown that the proposed method outperforms the conventional temporal matching method.