This paper describes the development of a novel walking assistance robot for the elderly and infirm. In the case of simple walking assistance devices, the walking safety and effectiveness are somewhat low; hence, caregivers are frequently required. The walking assistance robot developed in this research is capable of securely and conveniently assisting a walking user by using electric motors and various devices without a caregiver. The main features include the following. First, the walking safety is improved by using a pelvis supporter, and the robot is able to follow the user effectively by means of ergonomic motion sensors and electric powered wheels. Second, it is possible to adjust the load applied to the lower body by adjusting the height of the pelvis supporter. Finally, it is possible to inform the approximate distance and direction of any obstacle around the robot using the sounds and vibrations for the blind and the hearing impaired. The performance of the developed walking assistance robot was successfully verified using a walking assistance test in a narrow-corridor environment.