Purpose: The purpose of this study was to develop and evaluate effects of the integrative fidelity simulation curriculum. Methods: The integrative fidelity simulation curriculum was developed through meetings of experts based on nursing content. To test the application effect of simulation curriculum, a one group pre-post test design was applied. The simulation curriculum was applied with 149 nursing students who participated voluntarily. Results: In the application of satisfaction of the curriculum, learning interest in nursing and intrinsic motivation, nursing students had high scores in all evaluations. In addition, satisfaction of the curriculum had a significant positive correlation with learning interest in nursing and intrinsic motivation. Conclusion: The integrative fidelity simulation was an effective teaching tool for nursing students, and needs to develop more varied nursing simulation scenarios and curriculum.