Purpose: The purpose of this study was to identify factors in quality of life and to construct a model of quality of life in longevity region dwelling elders. Methods: Data were collected from January to July, 2010 through direct interviews and a self-reporting questionnaire survey with 171 subjects who were living at the S County (gun). The collected data were analyzed by using the SPSS/WIN 19.0 and AMOS 19.0 programs. Results: Economic status, social support, health behavior and depression were shown to have direct and total effects on quality of life and were statistically significant. Health status had indirect and total effects on quality of life and was statistically significant. And, self-efficacy had direct, indirect and total effects on quality of life and was statistically significant. These variables of the hypothetical model accounted for 41.4% of quality of life. Conclusion: In order to improve quality of life in longevity region dwelling elders, it is necessary to provide economic support and social support services in tandem with social welfare. And, we need to apply interventions strengthening self-efficacy, health behavior, and health status, and decreasing depression.