The thermal-flow characteristics of screw compressor were numerically investigated with various geometrical configurations of its coolant flow passage applied to the separate block for enhancing the heat transfer performance of it. The length ratio($L_s/D$=4.8, 5.6, 6.4) and thickness ratio(t/D=0.2, 0.4, 0.6) of the separate block in the flow passage of the water jacket were adopted to design parameters. Results showed that the pressure drop and heat transfer were increased as the length of separate block increases due to the flow separation and centrifugal force. The results were graphically depicted with various flow and geometrical conditions.