Objective: The purpose of this study was to examine natural groupings of the sub-factors of mother’s reaction to children’s negative emotions. The natural groupings were as follows; the emotion-coaching-reaction, the emotion-minimizing- reaction and oversensitive reaction. In addition, this paper also investigated individual differences in children’s emotion regulation by clusters of sub-factors of mother’s reaction to children’s negative emotions. Methods: The subjects of this study consisted of 318 children. The data were analyzed using cluster analysis and one-way ANOVA. Results: The results suggested four proper clusters, according to the characteristics of mother’s reaction to children’s negative emotions. Cluster 1 was categorized as ‘child centered-emotion coaching’, cluster 2 was categorized as ‘oversensitive- emotion coaching comorbid’, cluster 3 was categorized as ‘acceptionemotion minimizing confused’ and cluster 4 was categorized as ‘emotion minimizing- unsupporting.’ Additionally, the differences between Emotion regulations in each cluster showed distinct points of interest. In terms of the maladaptive emotion regulation, cluster 3 showed the highest level followed by cluster 4. And cluster 1 and 2 showed the lowest level. Conclusion/Implications: The results of this study helped to find a deeper understanding of the operation of specific clusters of mother’s reaction to children’s negative emotion and children’s emotion regulation.