The necessity of interdisciplinary research is becoming more and more urgent in the 21th century. That is to say, we must restore integrated study, study current in the 19th century so have to activate general and total research. Thus, at first, we ought to activate close cooperation and mutual exchange among various majors inside specific study. In addition, we have to cooperate and interact closely among independent studies. At last, if we complement insufficient side through close and mutual cooperation and exchange among independent studies and majors, we will be able to develop comprehensive and organic study system. STS are the space that humanities, social sciences and natural sciences cooperate and communicate mutually focusing on S&T, the main driving force of human society development since the 20th century. Therefore, STS have very comprehensive characteristic due to interdisciplinary cooperation. The research keynote of STS implies very innovative characteristic in breaking special research keynote, the dominant pattern of humanities and social sciences in the 20th century. Consequently, STS must play a leading role in contributing to the true development and progress of human society.