The purpose of this study is to identify the relationship of Career identification, Adaption to College and Self-esteem among male nursing students. the study results will be used as a basic data to enhance job satisfaction, career identification and self-esteem. The study design was a cross-sectional survey. The study participants were a total 300 male nursing students targeted from seven administrative districts. In order to analyze data was used statistics methods such as mean, standard deviation, t-test, ANOVA, and pearson correlation liner regression by SPSS WIN 20.0. Study measurements were the career identification nstrument, Student Adaptation to College Questionnaire (SACQ), and Rosenberg Self-Esteem Scale (RSEs).\nthe study results had shown significant corelation of career identification, adaption to college, and self-esteem and variables effecting on career identification were adaption to College, religion, and Self-esteem with explanation power of 39.3%. In order to enhance career identification among male nursing students, it is needed to develop systematic and specific programs of university for improving self-esteem and adaptation to college.