The purpose of this study was to assess the validity of the Face Stimulus Assessment (FSA) as a tool to screen adult women s depression tendency. To achieve this goal, the subjects selected were adult women aged 23 to 39, excluding college students, and data from a total of 300 subjects were analyzed by random sampling from cities A, B, and C. The research tools used were the FSA and the Integrated Korean Version of the Center for Epidemiologic Studies Depression Scale(CES-D). Data analysis was performed using SPSS 22.0, and the reliability was verified through the agreement between scorers and the test-retest reliability for the FSA. For validity, CES-D was administered to the study subjects to verify the concurrent validity and discriminant validity of the FSA. The results of this study are as follows. First, the reliability of the evaluation criteria in Figures 1 and 2 of the FSA stimulation according to the depressive tendency of adult women showed a very high level through the reliability between the graders and the test-retest reliability. These results imply that the FSA s evaluation criteria establish a relatively stable scoring index. Second, the FSA showed there was concurrent validity and discriminant validity in screening adult women s depressive tendencies. The study is meaningful in that the result show the FSA evaluation criteria were valid as a useful tool for screening adult women s depression. Based on these results the implications and limitations of this study were discussed.