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1811.

Systemic Injection of Lidocaine Induce Expression of c-fos mRNA and Protein in Adult Rat Brain

Han-JungChae, Jang-SookKang, Seoung-BumCho, Byung-GwanJin, Suk-JunWon, Byung-JooGwag, Hyung-RyongKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.1 9 69-74 (6 pages)

Han-JungChae, Jang-SookKang, Seoung-BumCho, Byung-GwanJin, Suk-JunWon, Byung-JooGwag, Hyung-RyongKim 저
...
- 3,000원
Both direct and indirect environmental stress to brain were increase the expression of transcription factor c-fos in various populations of neurons. In this study, we examined whether the intraperitoneal injections of lidocaine at doses inducing convulsion within 10 min increased the level of c-fos mRNA and protein in forebrain areas. In situ hybridization using [35S]UTP-labeled antisense c-fos, cRNA increased c-fos mRNA levels though hippocampal formation, piriform cortex, septum,...
1812.

Effects of Neonatal Footshock Stress on Glucocorticoid and 5- HT2A/2C Receptor Bindings and Exploratory Behavior

DongGooKim, SeoulLee, DongWonKang, JongSuLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.6 4 677-685 (9 pages)

DongGooKim, SeoulLee, DongWonKang, JongSuLim 저
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- 3,000원
To investigate the effects of neonatal stress on behavior and neurochemistry, rats were exposed to the footshock stress on postnatal day (PND) 14 or PNDs 14 and 21. Rats were exposed to uncontrollable electric shocks delivered to the floor with a constant current (0.8 mA) for 5 sec period. Daily sessions consisted of 60 trials on a random time schedule with an average of 55 sec. The first exposure to footshocks on PND 14 decreased body weight gain for 1 day. However, the second exposure to...
1813.

Effects of Dopamine and Haloperidol on Morphine-induced CREB and AP-1 DNA Binding Activities in Differentiated SH-SY5Y Human Neuroblastoma Cells

Soo-kyungKimGee-younKwon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.6 3 671-676 (6 pages)

Soo-kyungKimGee-younKwon 저
...
- 3,000원
In the present study, we first examined whether the changes in the DNA binding activities of the transcription factors, cAMP response element binding protein (CREB) and activator protein-1 (AP-1) mediate the long-term effects of morphine in differentiated SH-SY5Y human neuroblastoma cells. The increases in CREB and AP-1 DNA binding activities were time-dependent up to 6 days of morphine treatment (1, 4, and 6 days). However, the significant reduction in the DNA binding activities of CREB and...
1814.

Dual Action of d-Tubocurarine on Large-Conductance Ca2+-activated K+ Channels from Rat Brain Reconstituted into Planar Lipid Bilayer

SungkwonChungJungHoonShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.5 2 549-553 (5 pages)

SungkwonChungJungHoonShin 저
...
- 1,500원
Using the planar lipid bilayer method, we investigated the effect of d-tubocurarine (dTC) on the extracellular side of large-conductance Ca2+-activated K+ channel from rat brain. When the initial open probability (Po) of the channel was relatively high, dTC decreased channel activity in a concentration dependent manner. In contrast, when the initial Po was lower, sub-micro molar dTC increased channel activity by destabilizing the closed states of the channel. Further addition of dTC up to micro...
1815.

Distributional Patterns of Phospholipase C Isozymes in Heart and Brain of Spontaneously Hypertensive and Normotensive Rats

Ji-WoongChoi, Young-JinCho, SeokHoCha, Kweon-HaengLee, Sang-BokLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.4 5 385-392 (8 pages)

Ji-WoongChoi, Young-JinCho, SeokHoCha, Kweon-HaengLee, Sang-BokLee 저
...
- 3,000원
The phospholipase C (PLC)-mediated intracellular signal transduction pathway is considered to be involved in the regulation of blood pressure. However, little information is available concerning the distributional and functional significance of PLC in the genetic hypertensive rats. As the first step of knowing the role of PLC on hypertension, we investigated the distribution of 6 PLC isozymes (PLC-β1, -β3, -β4, -γ1, -γ2 and -δ1) in the heart and brain, which are concerned with...
1816.

Two Types of Voltage-dependent Outward Potassium Currents in Smooth Muscle Cells of Rabbit Basilar Atery

TongMookKang, InsukSo, DaeYongUhm, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 15 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 7 169-183 (15 pages)

TongMookKang, InsukSo, DaeYongUhm, KiWhanKim 저
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- 4,400원
We have investigated the two types of voltage-dependent outward potassium (K) currents, i.e. delayed rectifier K current (IK(V)) and 'A-like' transient outward K current (Ito) with patch-clamp technique in single smooth muscle cells (SMCs) isolated from rabbit basilar artery, and investigated the characteristics of them. The time-courses of activation were well fitted by exponential function raised to second power (n2) in IK(v) and fourth power (n4) in Ito. The activation, inactivation and...
1817.

Effect of Cisplatin on Sodium-Dependent Hexose Transport in LLC-PK1 Renal Epithelial Cells

SukKyuLee, JeeYeunKim, TaiHyunYu, KyoungRyongKim, KwangHyukKim, YangSaengPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.1 5 35-43 (9 pages)

SukKyuLee, JeeYeunKim, TaiHyunYu, KyoungRyongKim, KwangHyukKim, YangSaengPark 저
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- 3,000원
Cis-dichlorodiammine platinum II (Cisplatin), an effective chemotherapeutic agent, induces acute renal failure by unknown mechanisms. To investigate direct toxic effects of cisplatin on the renal proximal tubular transport system, LLC-PK1 cell line was selected as a cell model and the sugar transport activity was evaluated during a course of cisplatin treatment. Cells grown to confluence were treated with cisplatin for 60 min, washed, and then incubated for up to 5 days. At appropriate...
1818.

Alterations in Serum BDNF and GDNF Levels after 12 Weeks of Antidepressant Treatment in Female Outpatients with Major Depressive Disorder

Young-Min Park, Bun-Hee Lee 대한신경정신의학회 Psychiatry Investigation 6 Pages

대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 11 818-823 (6 pages)

Young-Min Park, Bun-Hee Lee 저
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- 3,000원
Objective_Some clinical studies have found alterations in the levels of serum brain-derived neurotrophic factor (BDNF) and glial cell line-derived neurotrophic factor (GDNF) after applying antidepressant treatment in patients with major depressive disorder (MDD). We evaluated the serum BDNF and GDNF levels before and after 12 weeks of antidepressant treatment in MDD outpatients. Methods_Serum BDNF and GDNF levels were measured in 23 female MDD outpatients at baseline and after 12 weeks of...
1819.

알코올 의존환자에서 갈근이 알코올 갈망과 대뇌 국소혈류량의 변화에 미치는 영향

강철중, 김명정, 김성곤, 김인주 대한신경정신의학회 신경정신의학 9 Pages

대한신경정신의학회 신경정신의학 1997, 제 36권 제 5호 8 861-869 (9 pages)

강철중, 김명정, 김성곤, 김인주 저
...
- 3,000원
요 약：알코올 의존 환자에서 갈근이 알코올 갈망을 감소시킨다는 보고가 있고 알코올 갈망에 관여하는 대뇌부위가 전두엽-시상-선조체-측좌핵을 포함하는 회로라는 학설이 있다. 저자는, 갈근이 이러한 부위의 혈류량에 어떤 영향을 미치는지 알아보기 위해 연구를 실시하였다. 알코올 의존으로 입원하여 급성중독과 금단증상에서 회복된 환자를 대상으로 실험 제1일에 알코올 갈망, 불안 및 기분을 측정한 후 단일광자광출전산화단층촬영술을 이용하여 양측 미상핵 두부, 양측 시상 및 양측 안와전두엽의 국소 혈류량을 측정하였다....
1820.

정신분열병의 인지치료

정영철 대한신경정신의학회 신경정신의학 10 Pages

대한신경정신의학회 신경정신의학 1998, 제 37권 제 2호 2 215-224 (10 pages)

정영철 저
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- 3,000원
지금까지의 정신증상 특히 망상과 환청에 대한 정신치료적 입장은 긍정도 부정도 아닌 중립적 태도로 충 분히 환자의 이야기를 들어주는 지지적 형태의 소극적 치료였다고 볼 수 있다. 그러나 인지치료는 직면이 아 닌 범위내에서 논리적이고 경험적 방법을 이용하여 적극적으로 증상의 공략을 추천하는 치료법인 것이다. 이 와같은 점에서 인지치료는 정신증상을 직접적으로 다루는 새로운 치료도구라는 의미가 있다. 또한 그 이론과 치료기법이 명료하고 손쉬워서 누구나 조금만 관심을 가지면 시행할 수 있는 강점도 가지고 있다....

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