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전체 선택해제
총 263건 검색
본문검색 결과만 보기
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Spinal Co-Administration of Ginsenosides with Morphine Prevents the Development of Opioid Tolerance and Attenuates Opioid Dependence
Choi. Seok, Jung. Se-Yeon, Nah. Jin-Ju, Ahn. Eun-Soon, Kim. Yoon-Hee, Nam. Ki-Yeul, Kim. Seok-Chang, Ko. Sung-Ryong, Rhim. Hyewhon, Nah. 고려인삼학회 Journal of ginseng research 8 Pages
고려인삼학회 Journal of ginseng research 1999, Vol.23 No.4 239-246 (8 pages)
백서를 이용하여 진세노사이드 흑은 모르핀을 척수강내 투여한 다음 tail-flick test를 통하여 진통 작용을 연구하였다. 또한, 진세노사이드를 모르핀과 함께 척수강내 장기 처리할 경우 모르핀에 의한 내성 및 의존성 유발에 미치는 영향을 연구하였다. 연구 결과, 척수강내 진세노사이드의 투여는 200 ${mu}g$/rat에서 약한 진통 작용이 있는 것으로 나타났다. 모르핀은 투여 농도에 의존적으로 좋은 진통 효능을 보여주었으며, $ED_50$은 1.2 ${mu}g/rat$인 것으로 나타났다. 그러나 진세노사이드의 모르핀을 함께 척수강내 투여할... -
Effects of opioid and non-opioid antagonists, pH and enzymes on Corchorus olitorius antinociception in mice
Zakaria. Zainul Amiruddin, Neelendran. M, Pubalan. S, Sulaiman. MR, Fatimah. CA 경희한의학연구센터 Oriental pharmacy and experimental medicine : OPEM 10 Pages
경희한의학연구센터 Oriental pharmacy and experimental medicine : OPEM 2006, Vol.6 No.3 186-195 (10 pages)
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Application of liquid chromatography tandem mass spectrometry for the simultaneous quantification of multiple non-opioid drugs in human plasma
Kim. Kwang-Youl, Kang. Ju-Hee, Kim. Cheol-Woo, Nam. Moon-Suk 대한독성유전단백체학회 Molecular & cellular toxicology 5 Pages
대한독성유전단백체학회 Molecular & cellular toxicology 2011, Vol.7 No.2 189-193 (5 pages)
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근거기반 암 환자 섬망간호 실무지침 개발과 효과 검증
박용숙, 구미옥 한국근거기반간호학회 근거와 간호 12 Pages
한국근거기반간호학회 근거와 간호 2013, 제 1권 제 1호 2 4-15 (12 pages)
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Stress and pain response after oligofructose induced-lameness in dairy heifers
Hedie A. Bustamante, Alfredo R. Rodr?guez, Daniel E. Herzberg, Marianne P. Werner 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 4호 3 405-411 (7 pages)
Lameness is one of the most painful conditions that affects dairy cattle. This study was conducted to evaluate clinical signs and plasma concentration of several pain and stress biomarkers after oligofructose-induced lameness in dairy heifers. Lameness was induced using an oligofructose overload model in 12 non-pregnant heifers. Clinical parameters and blood samples were obtained at 48 and 24 h and at 6, 12, 24, 36 and 48 h after induction of lameness. Clinical parameters included heart rate,... -
Sedative and analgesic effects of intravenous xylazine and tramadol on horses
Jong-pil Seo, Won-gyun Son, Sujin Gang, Inhyung Lee* 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2011, 제 12권 제 3호 12 281-286 (6 pages)
This study was performed to evaluate the sedative and analgesic effects of xylazine (X) and tramadol (T) intravenously (IV) administered to horses. Six thoroughbred saddle horses each received X (1.0 mg/kg), T (2.0 mg/kg), and a combination of XT (1.0 and 2.0 mg/kg, respectively) IV. Heart rate (HR), respiratory rate (RR), rectal temperature (RT), indirect arterial pressure (IAP), capillary refill time (CRT), sedation, and analgesia (using electrical stimulation and pinprick) were measured... -
Role of PKG-L-type calcium channels in the antinociceptive effect of intrathecal sildenafil
Woong Mo Kim, Myung Ha Yoon, Jin Hua Cui 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2010, 제 11권 제 2호 2 103-106 (4 pages)
Sildenafil increases the cyclic guanosine monophosphate (cGMP) by inhibition of a phosphodiesterase 5, thereby leading to an antinociceptive effect. The increased cGMP may exert the effect on an L-type calcium channel through the activation of protein kinase G (PKG). The purpose of this study was to examine the possible involvement of a PKG-L- type calcium channel on the effect of sildenafil at the spinal level. Catheters were inserted into the intrathecal space of male SD rats. Pain was induced...
