자료유형
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- 대한생리학회-대한약리학회(9)
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- 대한고령친화산업학회(1)
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- 대한기계학회론문집. TRANSACTIONS OF THE KOREAN SOCIETY OF MECHANICAL ENGINEERS. B. B(1)
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- 헬스커뮤니케이션연구(1)
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Investigation of empirical correlations on the determination of condensation heat transfer characteristics during downward annular flow of R134a inside a vertical smooth tube using artificial intelligence algorithms
Balcilar. Muhammet, Dalkilic. Ahmet Selim, Bolat. Berna, Wongwises. Somchai 대한기계학회 Journal of mechanical science and technology 19 Pages
대한기계학회 Journal of mechanical science and technology 2011, Vol.25 No.10 2683-2701 (19 pages)
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Effect of bidirectional internal flow on fluid.structure interaction dynamics of conveying marine riser model subject to shear current
Chen. Zheng-Shou, Kim. Wu-Joan 대한조선학회 International journal of naval architecture and ocean engineering 14 Pages
대한조선학회 International journal of naval architecture and ocean engineering 2012, Vol.4 No.1 57-70 (14 pages)
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섭취량 측정방법에 대한 근거기반간호 사례
김경희, 박정순, 김나현, 남수민, 박정옥, 서은정, 이현진, 김희준 한국근거기반간호학회 근거와 간호 6 Pages
한국근거기반간호학회 근거와 간호 2021, 제 9권 제 1호 4 27-32 (6 pages)
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멸균물품 유효기간 표준화를 위한 근거기반간호 사례
김윤희, 김경자, 이소연, 권정순, 장인실 한국근거기반간호학회 근거와 간호 4 Pages
한국근거기반간호학회 근거와 간호 2019, 제 7권 제 1호 4 19-22 (4 pages)
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The clinical efficacy of thoracolumbar fascia release for shoulder pain
Don Mo Choi, Ji Hye Jung 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2015, 제 4권 제 1호 10 55-59 (5 pages)
Objective: This study aimed to elucidate the effects of thoracolumbar fascia release (TLFR) on the degree of pain and disability in patients with shoulder pain. Design: Randomized control trial. Methods: Thirty subjects with shoulder pain participated in this study. They were allocated to TLFR group (n=15) and manual physical therapy (MPT) group (n=15). Shoulder pain and disability index (SPADI) and the score on the visual analogue scale (VAS) were measured before and after TLFR. Results: In the... -
Effect of gait training with additional weight on balance and gait in stroke patients
Seung Ho Shin, Mi Young Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 8 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2014, 제 3권 제 1호 10 55-62 (8 pages)
Objective: To study the effects of gait training with additional weight and gait training with non-additional weight on balance ability and gait ability in patients with chronic stroke through comparative analysis. Design: Randomized controlled trials. Methods: The subjects were divided randomly into two groups: additional weight group (AWG, n=12), and non-additional weight group (NAWG, n=10). Both groups received general physical therapy for 30 min in 1 session, 5 sessions per week during 6... -
Tissue distribution of marbofloxacin in pigs after a single intramuscular injection
Fan Yang, Yiming Liu, Zhili Li, Yuqin Wang, Baobao Liu, Zhensheng Zhao, Bianhua Zhou, Guoyong Wang 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 2호 6 169-173 (5 pages)
Tissue distribution of marbofloxacin was studied in pigs after a single intramuscular injection at 2.5 mg/kg body weight. Samples of plasma, muscle, liver, kidney, heart, lung, and muscle at the injection site were randomly collected from five pigs at 2, 6, 10, 24, 48, 72, and 96 h after administration. Marbofloxacin concentrations were determined by using high-performance liquid chromatography with ultraviolet detection and were subjected to non-compartmental analysis to obtain kinetic... -
Transcranial Doppler ultrasound analysis of resistive index in rostral and caudal cerebral arteries in dogs
Minho Seo, Hojung Choi, Kichang Lee, Mincheol Choi, Junghee Yoon 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2005, 제 6권 제 1호 9 61-66 (6 pages)
Transcranial Doppler (TCD) was carried out to determine the resistive index (RI) values of normal canine cerebral arteries and its reproducibility and to evaluate the change of cerebral vascular resistance following diuretics administration. RI values of rostral cerebral artery (RCA) were compared between fontanelle window and temporal window. Normal ranges and reproducibility of the RI values were examined in the rostal cerebral artery (RCA) and caudal cerebral artery (CCA). And after... -
Tricuspid valve dysplasia complicated with pulmonic regurgitation in a Cocker Spaniel dog
So Jeong Nam , Ran Choi , In Chul Park , Chang Baig Hyun , 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 7 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2008, 제 48권 제 4호 13 481-487 (7 pages)
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음악전공 대학생의 사회비교경향성과 교수자 지지가 주관적 안녕감에 미치는 영향
한국음악교육학회 음악교육연구 2020, 제 49권 제 1호 10 229-247 (19 pages)
본 연구는 음악전공 대학생들의 사회비교경향성이 주관적 안녕감에 미치는 영향을 살펴보고, 그 사이에서 학생들이 지각하는 교수자의 지지 유형이 조절효과를 나타내는지 확인하는 것을 목적으로 한다. 이를 위해 서울 및 경기 소재 음악대학생 253명을 대상으로 사회비교경향성, 주관적 안녕감 및 사회적 지지 척도를 사용하여 분석하였다. 분석 결과, 첫째, 음악전공 대학생의 사회비교경향성이 높을수록 주관적 안녕감의 하위요인 중 부정 정서를 유의하게 높이는 것으로 확인되었다. 둘째, 교수자 지지가 주관적 안녕감의 부정... -
이차구개 형태분화의 내적 조절유전자 규명
이재국, 장은하, 임양희, 김기병, 고승오, 조의식, 신효근 대한구순구개열학회 대한구순구개열학회지 16 Pages
대한구순구개열학회 대한구순구개열학회지 2007, 제 10권 1호 1 1-16 (16 pages)
이차구개는 발생과정에서 구개선반의 형성과 성장, 거상과 융합의 과정을 통해 형성된다. 이와 같은 이차구개의 형성과정은 미세한 분자유전학적 신호전달기전에 의해 조절되는 것으로 알려져 있어서, 신호전달과정에 관여하는 유전인자의 발현이상이 되면 정상적인 이차구개가 형성되지 못하고 구개파열이라는 선천성 기형이 발생된다. 구개파열의 유발인자들에 대한 많은 연구에도 불구하고 현재까지 정상적인 이차구개의 형성을 조절하는 분자유전학적 기전에 대해서는 명확히 알려져 있지 않다. 따라서 본 연구에서는 이차구개의... -
Analysis of the Baroreceptor and Vestibular Receptor Inputs in the Rostral Ventrolateral Medulla following Hypotension in Conscious Rats
YanLan, Huan-JunLu, XianJiang, Li-WeiLi, Yan-ZhaoYang, Guang-ShiJin, JooYoungPark, MinSunKim, ByungRimPark, Yuan-ZheJin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.2 11 159-165 (7 pages)
Input signals originating from baroreceptors and vestibular receptors are integrated in the rostral ventrolateral medulla (RVLM) to maintain blood pressure during postural movement. The contribution of baroreceptors and vestibular receptors in the maintenance of blood pressure following hypotension were quantitatively analyzed by measuring phosphorylated extracellular regulated protein kinase (pERK) expression and glutamate release in the RVLM. The expression of pERK and glutamate release in the... -
TRPV1 in Salivary Gland Epithelial Cells Is Not Involved in Salivary Secretion via Transcellular Pathway
SeulkiChoi, Yong-HwanShin, EunNamkoong, Sung-MinHwang, XinCong, GuangyanYu, KyungpyoPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.6 12 525-530 (6 pages)
of TRPV1 in salivary secretion using TRPV1 knock-out mice. There was no significant difference in the pilocarpine (PILO)-induced salivary flow rate between wild-type and TRPV1 knock-out mice. Saliva flow rate also showed insignificant change in the mice treated with PILO plus CAP compared with that in mice treated with PILO alone. Taken together, our results suggest that although TRPV1 is expressed in SGEC, it appears not to play any direct roles in saliva secretion via transcellular pathway. -
Effect of Vestibulosympathetic Reflex and Baroreflex on Expression of pERK in the Nucleus Tractus Solitarius following Acute Hypotension in Conscious Rats
XianJiang, YanLan, Yuan-ZheJin, JooYoungPark, ByungGeonPark, AbdulNasirAmeer, ByungRimPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.4 11 353-358 (6 pages)
Control of blood pressure is maintained by the interaction between the arterial baroreflex and vestibulosympathetic reflex during postural changes. In this study, the contributions of vestibular receptors and baroreceptors to the maintenance of blood pressure following acute hypotension were compared in terms of phosphorylated extracellular regulated protein kinase (pERK) expression in the nucleus tractus solitaries (NTS). Expression of pERK in the NTS was measured in conscious rats that had... -
Disappearance of Hypoxic Pulmonary Vasoconstriction and O2-Sen-sitive Nonselective Cationic Current in Arterial Myocytes of Rats Under Ambient Hypoxia
HaeYoungYoo, SungJoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.5 13 463-468 (6 pages)
Acute hypoxia induces contraction of pulmonary artery (PA) to protect ventilation/perfusion mismatch in lungs. As for the cellular mechanism of hypoxic pulmonary vasoconstriction (HPV), hypoxic inhibition of voltage-gated K+ channel (Kv) in PA smooth muscle cell (PASMC) has been suggested. In addition, our recent study showed that thromboxane A2 (TXA2) and hypoxia-activated nonselective cation channel (INSC) is also essential for HPV. However, it is not well understood whether HPV is maintained... -
Additive Role of the Vestibular End Organ and Baroreceptors on the Regulation of Blood Pressure in Rats
YanLan, Yan-ZhaoYang, XianJiang, Li-WeiLi, Guang-ShiJin, MinSunKim, ByungRimPark, Yuan-ZheJin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.4 15 367-373 (7 pages)
Contribution of the vestibular end organ to regulation of arterial pressure was quantitatively compared with the role of baroreceptors in terms of baroreflex sensitivity and c-Fos protein expression in the rostral ventrolateral medulla (RVLM). Baroreflex sensitivity and c-Fos protein expression in the RVLM were measured in conscious rats that had undergone bilateral labyrinthectomy (BL) and/or baroreceptor unloading. BL attenuated baroreflex sensitivity during intravenous infusion of sodium... -
5,8-Dimethoxy-2-Nonylamino-Naphthalene-1,4-DioneInhibitsVascular Smooth Muscle Cell Proliferation by Blocking Autophosphorylation of PDGF-Receptor β
YohanKim, Jung-JinLee, Sang-GilLee, Sang-HyukJung, Joo-HuiHan, SoYoungYang, , EunjuYun, Gyu-YongSong, Chang-SeonMyung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.3 4 203-208 (6 pages)
As the abnormal proliferation of vascular smooth muscle cells (VSMCs) plays a critical role in the development of atherosclerosis and vascular restenosis, a candidate drug with antiproliferative properties is needed. We investigated the antiproliferative action and underlying mechanism of a newly synthesized naphthoquinone derivative, 5,8-dimethoxy-2-nonylamino-naphthalene-1,4-dione (2-nonylamino- DMNQ), using VSMCs treated with platelet-derived growth factor (PDGF). 2-Nonylamino-DMNQ inhibited... -
Protein Kinase C Activates ATP-sensitive Potassium Channels in Rabbit Ventricular Myocytes
NariKim, JaeBoumYoum, HyunJoo, HyungkyuKim, EuiyongKim, JinHan 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.4 1 187-194 (8 pages)
Several signal transduction pathways have been implicated in ischemic preconditioning induced by the activation of ATP-sensitive K (KATP) channels. We examined whether protein kinase C (PKC) modulated the activity of KATP channels by recording KATP channel currents in rabbit ventricular myocytes using patch-clamp technique and found that phorbol 12,13-didecanoate (PDD) enhanced pinacidil-induced KATP channel activity in the cell-attached configuration; and this effect was prevented by... -
Pharmacological Action Mechanism(s) of Vasodilator Effect of Calcitonin Gene-related Peptide in Rat Basilar Arteries
임병용(Byung Yong Rhim), 홍선화(Sun Hwa Hong), 김치대(Chi Dae Kim), 이원석(Won Suk Lee), 김동헌(Dong Heon Kim), 홍기환(Ki Whan Hong) 대한약리학회 대한약리학잡지 12 Pages
대한약리학회 대한약리학잡지 1996, 제 32권 제 1호 5 39-50 (12 pages)
the ratio of F340/F380 ([Ca2+]i) as a function of the force induced by U46619, and the results were compared with those obtained in the presence of CGRP. The curves obtained in the presence of CGRP (30 and 100 nM) were significantly moved to downward without right shift of the curves suggesting that CGRP inhibited the U46619-induced contraction only by mediation of reduction in [Ca2+]i with out any change in the sensitivity of contractile apparatus to Ca2+. The CGRP-induced attenuation of... -
뇌혈류 자가조절에 대한 Endothelium-derived Relaxing Factor의 역할
홍기환(Ki Whan Hong), 유성숙(Sung Suk Yu), 임병용(Byung Yong Rhim) 대한약리학회 대한약리학잡지 12 Pages
대한약리학회 대한약리학잡지 1995, 제 31권 제 1호 4 27-38 (12 pages)
본 연구에서는 콜린성 기전에 반응하여 분비되는 내피 의존성 이완물질(endothelium-derived relaxing factor, EDRF)나 nitric oxide(NO)가 마취 흰쥐의 뇌혈류 자가조절기전에 관여할 가능성을 관찰하였다. Acetylcholine(10-9-10-6M)을 포함한 mock 뇌척수액(CSF)을 관류시 뇌연막 동맥은 농도에 의존하여 이완반응 나타내었고(평균; 19.3 ± 1.7μm, n=36), 이러한 이완반응은 N{\omega}-nitro-L-arginine(L-NNA, 10-5M)에 의해서 억제되었을 뿐 아니라 methylene blue(10-6M)나 oxyhemoglobin(10-6M)에 의하여도 억제되었다. 한편... -
The Action of Ginkgo Bibloba Extract in the Isolated Rabbit Corpus Cavernosum
Chung, Woo-Sik, Choi, Young-Deuk, Park, Young-Yo, Hah, Jong-Sik 대한생리학회 대한생리학회지 8 Pages
대한생리학회 대한생리학회지 1995, 제 29권 제 1호 6 61-68 (8 pages)
The extract of Ginkgo bibloba (EGb) is a complex mixture of natural products from the Ginkgo leaves and clinically used for the treatment of cerebral and peripheral circulatory disturbances due to its combined activity of several vasoactive principles. In this study we investigated the action of EGb and its mechanism in isolated rabbit corporal smooth muscle to evaluate the possibility of using this material as a pharmacoerecting agent. Strips of rabbit corpus cavernosum were mounted in organ... -
Calcium Balance in the Heart -Annual Review Lecture, October 13, 1990-
Noble, Denis 대한생리학회 대한생리학회지 16 Pages
대한생리학회 대한생리학회지 1991, 제 25권 제 1호 1 1-16 (16 pages)
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토끼 태반을 통한 Li+ 이동에 관한 연구
성호경(Sung, Ho-Kyung), 김전(Kim, Jun) 대한생리학회 대한생리학회지 8 Pages
대한생리학회 대한생리학회지 1984, 제 18권 제 1호 1 1-8 (8 pages)
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Take-all of Wheat and Natural Disease Suppression: A Review
한국식물병리학회 The Plant Pathology Journal 11 Pages
한국식물병리학회 The Plant Pathology Journal 2013, 29권 2호 2 125-135 (11 pages)
In agro-ecosystems worldwide, some of the most important and devastating diseases are caused by soil-borne necrotrophic fungal pathogens, against which crop plants generally lack genetic resistance. However, plants have evolved approaches to protect themselves against pathogens by stimulating and supporting specific groups of beneficial microorganisms that have the ability to protect either by direct inhibition of the pathogen or by inducing resistance mechanisms in the plant. One of the best... -
Gaussian Profile based Vehicular Mobility Modeling
Brijesh Kumar Chaurasia, Shekhar Verma, G. S. Tomar 인문사회과학기술융합학회 예술인문사회융합멀티미디어논문지 18 Pages
인문사회과학기술융합학회 예술인문사회융합멀티미디어논문지 2011, 제 1권 제 2호 2 59-76 (18 pages)
The driving behavior of a person is influenced by a multitude of local and global factors. These include nature of the driver, distance between the source and destination, condition of the road selected by the driver, traffic conditions, time constraints, lane changing, overtaking actions, safe distance, reaction time etc. are vital for modeling the mobility of a vehicle and are largely determined by the driving behavior. In this paper, a profile based model has been proposed to define the... -
65세 이상 택시운송업 종사자에 한국형 자가보고식 안전운전행동평가(K-SDBM)연구
이혜진, 구영화 대한고령친화산업학회 대한고령친화산업학회지 12 Pages
대한고령친화산업학회 대한고령친화산업학회지 2015, 제 7권 1호 3 17-28 (12 pages)
서론 본 연구는 고령화 사회에 따라 65세 이상 택시운송업 종사자를 대상으로 한국형 자가 보고식 운전행 동측정도구(K-SDBM)를 사용하여 운전 시 발생할 수 있는 사고 특성과 위험요인에 대해 알아보고자 하였다. 연구방법 2015년 2월 1일부터 3월 30일까지 4주 동안 부산소재지 택시운송업 종사자 32명을 대상으로 한국형 자가 보고식 운전행동측정도구(K-SDBM)를 실시하였다. 연구결과 1. 집중이 요구되는 운전 상황 모든 요인에서 50%이상의 응답자가 조금어렵다로 높게 나타났다. 2. 일반적 운전기술에서는 흐린 차선, 울퉁불퉁한 길... -
Survival strategies of the economic recession in the hospitality industry
Won, Chol-Shik 한국관광서비스학회 관광서비스연구 12 Pages
한국관광서비스학회 관광서비스연구 2013, 제 12권 제 1호 (통권 23권) 3 41-52 (12 pages)
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College Students’ Self-Concepts and Attitude toward Advertising; The Relationships among the Body-Esteem, Social Comparison, and the Perception about Diet Advertising
Hyunjae Yu 한국헬스커뮤니케이션학회 헬스커뮤니케이션연구 43 Pages
한국헬스커뮤니케이션학회 헬스커뮤니케이션연구 2014, Vol.11 3 75-117 (43 pages)
There have been many studies dealing with the relationships between selfperceptions and the perceptions of advertising. However, research that focused specifically on diet advertising, which has recently seen a dramatic increase in our society, has been scarce. One can assume that people’s perceptions of diet advertising may be influenced by how they think about their own bodies or by the extent to which they compare their own bodies with those of others. For a more comprehensive understanding... -
Eye on the Future: Diverse Family Language Policy in Three Singaporean Malay Homes with Preschool Children
Chen-Chen Cheng 환태평양유아교육연구학회 Asia-Pacific journal of research in early childhood education 23 Pages
환태평양유아교육연구학회 Asia-Pacific journal of research in early childhood education 2020, Vol.14 No.1 6 125-147 (23 pages)
Singapore’s bilingual education policy mandates children study English and a mother-tongue in school. To understand the language shift from Malay to English in Malay homes from the perspective of family language policy, this paper reports on the diverse language ideologies and practices of three Singaporean Malay mothers of preschool children. The in-depth interviews were conducted in 2013- 2014 and transcribed verbatim by a bilingual English-Malay transcriptionist. Although the mothers were of... -
일하고 놀까? 놀고 일할까? : 행복, 관계 그리고 여가 우선 선택
이국희, 최인철 한국여가문화학회 여가학연구 25 Pages
한국여가문화학회 여가학연구 2018, vol.16 no.1 2 29-53 (25 pages)
본 연구는 일을 여가보다 우선하는 전반적인 경향성에도 불구하고, 때에 따라 여가를 먼저 즐길 줄 아는 사람들과 관련 있는 심리적 특성이 무엇인지를 확인하기 위해 이루어졌다. 그리고 다양한 선행연구에 기초하여 주관적 행복 수준이 여가를 일보다 우선하는 선택과 관련이 있을 것이라고 가정하였다. 이를 확인하기 위해 216명의 직장인들을 대상으로 얼마나 행복한지, 최근 3개월 내에 일보다 여가를 우선한 경험이 있는지, 그 경험에 함께한 사람이 있었는지, 그리고 현재 일-여가 비율은 어느 정도 인지에 대한 온라인 설문을... -
인공용승구조물 설치에 의한 유동변화 ( I )
김동선, 황석범, Kim. Dong-Sun, Hwang. Suk-Bum 해양환경안전학회 海洋環境安全學會誌 6 Pages
해양환경안전학회 海洋環境安全學會誌 2006, Vol.12 No.4 301-306 (6 pages)
인공용승구조물 설치해역의 구조물에 의한 유동분포를 파악하기 위하여 ADCP(Acoustic Doppler Current Profiler)를 이용한 정선관측을 2006년 5월 4일(소조기) 및 5월 30일(대조기)에 실시하였다. 동서-남북(un-component) 유동성분의 분석결과, 조시에 따른 흐름이 전반적으로 남동류가 우세하게 나타났으며 구조물 주변역의 표층에서 수심 $30sim40m$까지의 유동과 이심에서의 유동이 서로 다르게 나타났다. 연직유동성분(w-component)은 소조기시 구조물 주변해역과 서쪽역에서는 상승류의 흐름이 나타났고 남쪽역, 북쪽역 및... -
중력방향과 대향류인 저속 원형노즐제트 충돌에 의한 일정 두께 하향 등온원형평판에서의 열전달 현상
엄용균, Eom. Yongkyoon 한국수소및신에너지학회 한국수소 및 신에너지학회 논문집 10 Pages
한국수소및신에너지학회 한국수소 및 신에너지학회 논문집 2014, Vol.25 No.4 449-458 (10 pages)
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원형튜브내에서 이동중인 고체입자층의 열전달 특성연구
이금배, 박상일 대한기계학회 大韓機械學會論文集 8 Pages
대한기계학회 大韓機械學會論文集 1994, Vol.18 No.6 1551-1558 (8 pages)
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Application of ventriculoperitoneal shunt as a treatment for hydrocephalus in a dog with syringomyelia and Chiari I malformation
Heejaung Kim, Kazuhito Itamoto, Malaika Watanabe, Munekazu Nakaichi, Yasuho Taura 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 2호 19 203-206 (4 pages)
A twenty-month-old Chihuahua male dog was presented to us suffering with ataxia. Based on the physical examination, X-ray and magnetic resonance imaging (MRI) examinations, we diagnosed the dog with hydrocephalus, Chiari I malformation and syringomyelia. Treatment consisted of internal medical treatment and the placement of a ventriculoperitoneal (VP) shunt. The ventricular dilatation was relieved and the dog improved neurologically; however, the Chiari I malformation and syringomyelia remained... -
Functional identification of protein phosphatase 1-binding consensus residues in NBCe1-B
KyuPilLee, HyunJinKim, DongkiYang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.1 10 91-99 (9 pages)
Protein phosphatase 1 (PP1) is involved in various signal transduction mechanisms as an extensive regulator. The PP1 catalytic subunit (PP1c) recognizes and binds to PP1-binding consensus residues (FxxR/KxR/K) in NBCe1-B. Consequently, we focused on identifying the function of the PP1-binding consensus residue, 922FMDRLK927, in NBCe1-B. Using site-directed mutagenesis and co-immunoprecipitation assays, we revealed that in cases where the residues were substituted (F922A, R925A, and K927A) or...


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