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Aging-related alterations in the body metabolism of companion animals
Ji Houn Kang 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 춘계학술심포지움 14 99-99 (1 pages)
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풍요로운 환경(Environmental Enrichment)이 파킨슨병 동물 모델의 운동기능 향상에 미치는 효과
강경아, 한상숙, 김경희, 김연정 한국기초간호학회 Journal of Korean Biological Nursing Science 8 Pages
한국기초간호학회 Journal of Korean Biological Nursing Science 2008, Vol.10 No.2 10 176-183 (8 pages)
파킨슨병(Parkinson’s Disease, PD)은 강직(rigidity), 운 동완서(bradykinesia), 진전(tremor) 등의 임상적 증상을 특 징으로 하는 진행성, 신경퇴행성 질환으로 50대 이후에 주로 발병하여 60대 이후에서는 최고의 발병률을 보이고 있다. 미 국의 경우 연간 인구 100,000명당 256명의 비율로 발병하며 거의 150만 명이 파킨슨병으로 진단을 받았고 매년 60,000명 이 새로 진단을 받고 있다. 국내의 경우 18세 이상의 인구에서 파킨슨병 유병률이 인구 100,000명당 374명으로 남자의 유병률이 1.7배 높았으며 70 세 이상의 경우 자세... -
The dependence of nitric oxide synthase inhibition caused by cigarette smoking extracton the cellular aging of bovine aortic endothelial cells
Le. VuQuynhAnh, Kim. Yang-Hoon, Min. Jiho 환경독성보건학회 Environmental health and toxicology : EHT 2 Pages
환경독성보건학회 Environmental health and toxicology : EHT 2014, Vol.29 No.6 10-11 (2 pages)
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장애인직업재활시설을 이용하는 중·고령 발달장애인이 인식하는 잘 늙어감(Well-aging)에 대한 인식유형 연구
임효순, 윤정란 한국장애인복지학회 한국장애인복지학 29 Pages
한국장애인복지학회 한국장애인복지학 2019, Vol.44 7 183-211 (29 pages)
이 연구는 장애인직업재활시설을 이용하고 있는 중·고령 발달장애인 당사자가 인식하는 잘 늙어감에 대한 인식유형을 탐색하고 그 특성을 밝히려고 시도되었다. 이를 위해 Q 방법론을 활용하여 문헌 고찰과 심층 면접을 통해 추출한 30개의 항목을 Q 표본으로, 장애인직업재활시설을 이용하고 있는 40세 이상 중·고령 발달장애인 37명을 P 표본으로 선정하여 실증적으로 고찰하였다. 분석결과, 중·고령 발달장애인이 인식하는 잘 늙어감에 대한 인식유형은 ‘긍정적 마인드 추구형’, ‘사회적 참여 지향형’, ‘일상의 안녕 추구형’,... -
가치유형에 따른 행복감의 차이와 가치유형 결정에 영향을 미치는 요인
한국종교교육학회 종교교육학연구 2022, 제 70권 1 1-28 (28 pages)
연구 목적 본 연구의 목적은 자기고양가치와 자기초월가치의 수준을 토대로 가치를 유형화 한 후, 각 유형에 따라 행복감에 어떤 차이가 있는지를 밝히고 행복감이 높은 가치유형을 결 정함에 있어 영향을 미치는 개인적 요인과 가정적 배경을 탐색하는 데 있다. 연구 내용 본 연구는 10대에서 90대까지의 한국인의 가치를 조사한 KGSS 2021년 자료를 활용하여 변량분석과 이분형 로지스틱 회귀분석을 실시하였다. 이를 통해, 첫째는 한국인의 가치유형을 자기고양가치와 자기초월가치의 평균값을 기준으로 네 가지 유형으로 분류하였고,... -
근거기반 암 환자 섬망간호 실무지침 개발과 효과 검증
박용숙, 구미옥 한국근거기반간호학회 근거와 간호 12 Pages
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작업적 역할: 고찰
공명자, 정민예 한국노인작업치료학회 한국노인작업치료학회지 10 Pages
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목적: 본 연구의 손상과 장애를 가진 사람들의 사회적 복귀 측면에서의 역할과 그 역할 수행을 알아보고자 문헌을 통해 작업적 역할 개념, 의미와 종류들을 비교하고, 향후 재활치료에서 대상자들의 역할 수행에 대한 이해를 돕고자 한다. 연구방법: 연세대학교 학술정보원 홈페이지와 Google Scholar에서 “role”, “activity or occupation”, “occupational therapy”을 조합하여 역할에 대한 논문과 도서를 검색하여 고찰하였다. 결과: 역할에 관련된 작업치료 이론은 인간 수행의 생태학, 사람-환경-작업 모델, 사람중심의 작업... -
Discriminative validity of the timed up and go test for community ambulation in persons with chronic stroke
Seung Heon An, Dae-Sung Park, Ji Young Lim 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2017, 제 6권 제 4호 4 176-181 (6 pages)
Objective: The timed up and go (TUG) test is method used to determine the functional mobility of persons with stroke. Its reliability, validity, reaction rate, fall prediction, and psychological characteristics concerning ambulation ability have been validated. However, the relationship between TUG performance and community ambulation ability is unclear. The purpose of this study was to investigate whether the TUG performance time could indicate community ambulation levels (CAL) differentially... -
Dual task interference while walking in chronic stroke survivors
Joon-Ho Shin, Hyun Choi, Jung Ah Lee, Seon-deok Eun, Do-hoon Koo, Jae-Ho Kim, Sol Lee, Ki-Hun Cho 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2017, 제 6권 제 3호 5 134-139 (6 pages)
Objective: Dual-task interference is defined as decrements in performance observed when people attempt to perform two tasks concurrently, such as a verbal task and walking. The purpose of this study was to investigate the changes of gait ability according to the dual task interference in chronic stroke survivors. Design: Cross-sectional study. Methods: Ten chronic stroke survivors (9 male, 1 female; mean age, 55.30 years; mini mental state examination, 19.60; onset duration, 56.90 months)... -
Microglial involvement in the development of olfactory dysfunction
Yoojin Seo, Hyung-Sik Kim, Kyung-Sun Kang 대한수의학회 Journal of Veterinary Science 12 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 3호 1 319-330 (12 pages)
Olfactory impairment is the most common clinical manifestation among the elderly, and its prevalence increases sharply with age. Notably, growing evidence has shown that olfactory dysfunction is the first sign of neurodegeneration, indicating the importance of olfactory assessment an early marker in the diagnosis of neurological disorders. In this review, we describe the nature of olfactory dysfunction and the advantage of using animal models in olfaction study, and we include a brief... -
Retrospective evaluation of circulating thyroid hormones in critically ill dogs with systemic inflammatory response syndrome
Massimo Giunti, Roberta Troia, Mara Battilani, Luciana Giardino, Francesco Dondi, Giulia Andreani, Federico Fracassi 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 4호 10 471-477 (7 pages)
Critical illness can be associated with transient alterations in circulating thyroid hormone concentrations, indicating the presence of non-thyroidal illness (NTI). NTI is well described in humans, but there are few reports on its occurrence and prognostic significance in dogs. This retrospective study assessed the occurrence of NTI in a population of dogs with systemic inflammatory response syndrome (SIRS) and investigated its association with disease severity (APPLEfast scores). A total of 41... -
Apoptosis in response to heat stress is positively associated with heat-shock protein 90 expression in chicken myocardial cells in vitro
Xiao-Hui Zhang, Hong Wu, Shu Tang, Qiao-Ning Li, Jiao Xu, Miao Zhang, Ya-Nan Su, Bin Yin, Qi-Ling Zhao, Nicole Kemper, Joerg Har 대한수의학회 Journal of Veterinary Science 12 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 2호 2 129-140 (12 pages)
To determine heat-shock protein (Hsp)90 expression is connected with cellular apoptotic response to heat stress and its mechanism, chicken (Gallus gallus) primary myocardial cells were treated with the Hsp90 promoter, aspirin, and its inhibitor, geldanamycin (GA), before heat stress. Cellular viability, heat-stressed apoptosis and reactive oxygen species level under different treatments were measured, and the expression of key proteins of the signaling pathway related to Hsp90 and their... -
Learning, memory and exploratory similarities in genetically identical cloned dogs
Chi Won Shin, Geon A Kim, Won Jun Park, Kwan Yong Park, Jeong Min Jeon, Hyun Ju Oh, Min Jung Kim, Byeong Chun Lee 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 4호 16 563-567 (5 pages)
Somatic cell nuclear transfer allows generation of genetically identical animals using donor cells derived from animals with particular traits. To date, few studies have investigated whether or not these cloned dogs will show identical behavior patterns. To address this question, learning, memory and exploratory patterns were examined using six cloned dogs with identical nuclear genomes. The variance of total incorrect choice number in the Y-maze test among cloned dogs was significantly lower... -
Effects of aluminum on the reduction of neural stem cells, proliferating cells, and differentiating neuroblasts in the dentate gyrus of D-galactose-treated mice via increasing oxidative stress
Sung Min Nam, Jong Whi Kim, Dae Young Yoo, Woosuk Kim, Hyo Young Jung, Jung Hoon Choi, In Koo Hwang, Je Kyung Seong, Yeo Sung Yo 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 2호 1 127-136 (10 pages)
Aluminum (Al) accumulation increases with aging, and long-term exposure to Al is regarded as a risk factor for Alzheimer’s disease. In this study, we investigated the effects of Al and/or D-galactose on neural stem cells, proliferating cells, differentiating neuroblasts, and mature neurons in the hippocampal dentate gyrus. AlCl3 (40 mg/kg/day) was intraperitoneally administered to C57BL/6J mice for 4 weeks. In addition, vehicle (physiological saline) or D-galactose (100 mg/kg) was... -
Rapamycin treatment during in vitro maturation of oocytes improves embryonic development after parthenogenesis and somatic cell nuclear transfer in pigs
Joohyeong Lee, Jong-Im Park, Jung Im Yun, Yongjin Lee, Hwanyul Yong, Seung Tae Lee, Choon-Keun Park, Sang-Hwan Hyun, Geun-Shik L 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 3호 16 373-380 (8 pages)
This study was conducted to investigate the effects of rapamycin treatment during in vitro maturation (IVM) on oocyte maturation and embryonic development after parthenogenetic activation (PA) and somatic cell nuclear transfer (SCNT) in pigs. Morphologically good (MGCOCs) and poor oocytes (MPCOCs) were untreated or treated with 1 nM rapamycin during 0–22 h, 22–42 h, or 0–42 h of IVM. Rapamycin had no significant effects on nuclear maturation and blastocyst formation... -
Normal clinical electroretinography parameters for poodle, Labrador retriever, Thai ridgeback, and Thai Bangkaew
Metita Sussadee, Janjira Phavaphutanon, Kornchai Kornkaewrat, Aree Thayananuphat 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 1호 9 67-74 (8 pages)
The purpose of the present study was to establish normal electroretinogram (ERG) parameters using 56 normal eyes of four dog breeds common in Thailand: poodle, Labrador retriever, Thai ridgeback, and Thai Bangkaew. Standard ERG findings were bilaterally recorded using a handheld multi-species ERG unit with an ERG-jet lens electrode for 28 dogs under preanesthesia with diazepam, anesthesia with propofol, and anesthesia maintenance with isoflurane. There were significant... -
Detection of Corynebacterium bovis infection in athymic nude mice from a research animal facility in Korea
Tae-Hyoun Kim, Dong-Su Kim, Ju-Hee Han, Seo-Na Chang, Kyung-Sul Kim, Seung-Hyeok Seok, Dong-Jae Kim, Jong-Hwan Park, Jae-Hak Par 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 4호 13 583-586 (4 pages)
Corynebacterium (C.) bovis infection in nude mice causes hyperkeratosis and weight loss and has been reported worldwide but not in Korea. In 2011, nude mice from an animal facility in Korea were found to have white flakes on their dorsal skin. Histopathological testing revealed that the mice had hyperkeratosis and Gram-positive bacteria were found in the skin. We identified isolated bacteria from the skin lesions as C. bovis using PCR and 16S rRNA sequencing. To the best of our knowledge, this... -
Comparison of arylalkylamine N-acetyltransferase and melatonin receptor type 1B immunoreactivity between young adult and aged canine spinal cord
Ji Hyeon Ahn, Joon Ha Park, In Hye Kim, Jae-Chul Lee, Bing Chun Yan, Min Sik Yong, Choong Hyun Lee, Jung Hoon Choi, Ki-Yeon Yoo, 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 3호 1 335-342 (8 pages)
in aged dog spinal neurons compared to young adult spinal neurons. MT2-specific immunoreactivity was found in the cytoplasm of spinal neurons, and was predominantly increased in the margin of the neuron cytoplasm in aged spinal cord compared to that in the young adult dogs. These increased levels of AANAT and MT2 immunoreactivity in aged spinal cord might be a feature of normal aging and associated with a feedback mechanism that compensates for decreased production of melatonin during aging. -
Common allergens of atopic dermatitis in dogs: comparative findings based on intradermal tests
Ha-Jung Kim, Min-Hee Kang, Hee-Myung Park* 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2011, 제 12권 제 3호 13 287-290 (4 pages)
Intradermal tests were performed on 58 dogs diagnosed with atopic dermatitis from 2004∼2008 at the Veterinary Medical Teaching Hospital of Konkuk University, Korea. To compare the allergen distribution observed in the present investigation to the results from other studies conducted in Korea and elsewhere, the allergens were grouped according to their kinds. There was no significant difference in gender distribution among the dogs. The most common breeds among the 58 dogs were Maltese (n =... -
Comparison of the age-related porcine endogenous retrovirus (PERV) expression using duplex RT-PCR
Hyoung Joon Moon, Hye Kwon Kim, Seong Jun Park, Chul Seung Lee, Dae Sub Song, Bo Kyu Kang, Bong Kyun Park* 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2009, 제 10권 제 4호 7 317-322 (6 pages)
Porcine endogenous retroviruses (PERVs) are members of family Retroviridae, genus Gamma retrovirus, and transmitted by both horizontally and vertically like other endogenous retroviruses (ERVs). PERV was initially described in the 1970s having inserted its gene in the host genome of different pig breeds, and three classes, PERV-A, PERV-B, and PERV-C are known. The therapeutic use of living cells, tissues, and organs from animals called xenotransplantation might relieve the limited supply of... -
Induction of oxidative stress and lipid peroxidation in rats chronically exposed to cypermethrin through dermal application
Rajinder Raina, Pawan K. Verma, N. K. Pankaj, Shahid Prawez* 대한수의학회 Journal of Veterinary Science 3 Pages
대한수의학회 Journal of Veterinary Science 2009, 제 10권 제 3호 12 257-259 (3 pages)
Present study was undertaken to study the effect of cypermethrin on oxidative stress after chronic dermal application. The insecticide was applied dermally at 50 mg/kg body weight in different groups of Wistar rats of either sex weighing 150∼200 g. Significant (p ＜ 0.05) increase in catalase activity was observed after 30 days of exposure. However, the superoxide dismutase activity declined significantly after 60 days of exposure. The activity of glutathione peroxidase and blood... -
Immunohistochemical identification and quantitative analysis of cytoplasmic Cu/Zn superoxide dismutase in mouse organogenesis
Jung-Min Yon, In-Jeoung Baek, Se-Ra Lee, Mi-Ra Kim, Beom Jun Lee, Young Won Yun, Sang-Yoon Nam 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 3호 2 233-240 (8 pages)
Cytoplasmic Cu/Zn superoxide dismutase (SOD1) is an antioxidant enzyme that converts superoxide to hydrogen peroxide in cells. Its spatial distribution matches that of superoxide production, allowing it to protect cells from oxidative stress. SOD1 deficiencies result in embryonic lethality and a wide range of pathologies in mice, but little is known about normal SOD1 protein expression in developing embryos. In this study, the expression pattern of SOD1 was investigated in post-implantation... -
Hepatocellular adenoma in a Eurasian otter (Lutra lutra)
Il-Hong Bae, Bidur Pakhrin, Hyang Jee, Nam-Shik Shin, Dae-Yong Kim 대한수의학회 Journal of Veterinary Science 3 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 1호 16 103-105 (3 pages)
A 7-year-old female Eurasian otter (Lutra lutra) at the Seoul Grand Park, Korea, died after displaying depression, anorexia, weight loss and rough skin for several days. At necropsy, a solitary friable round mass, which was approximately 12 × 9 × 5 cm and mottled dark red and yellow, was found bulging from the right hepatic lobe. Microscopically, the nonencapsulated, poorly circumscribed mass was composed of solid sheets of neoplastic hepatocytes. In addition, numerous small tan foci, ranging... -
Molecular analysis of hprt mutation in B6C3F1 mice exposed to ozone alone and combined treatment of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone and/or dibutyl phthalate for 32 and 52 weeks
Min Young Kim, Hyun Woo Kim, Jin Hong Park, Jun Sung Kim, Hwa Jin, Seo Hyun Moon, Kook Jong Eu, Hyun Sun Cho, Gami Kang, Yoon Sh 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2004, 제 5권 제 4호 14 379-385 (7 pages)
Potential toxicological interactions of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and/or dibuthyl phthalate (DBP) on ozone were investigated after 32- and 52-wk exposures using hprt mutation assay. Male and female B6C3F1 mice exposed to ozone (0.5 ppm), NNK (1.0 mg/kg), DBP (5,000 ppm), and two or three combinations of these toxicants 6 h per day for 32- and 52-wk showed increases in the frequencies of TG rlymphocytes compared to the control groups. Additive interactions were... -
Biological Rhythm in Livestock
Piccione Giuseppe and Caola Giovanni 대한수의학회 Journal of Veterinary Science 13 Pages
대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 3호 1 145-157 (13 pages)
and of sensitivity and resistance to many environmental agents are often quite large and offer not only new insight into animal physiology and pathology but also diagnostic possibilities and therapeutic advantages. Chronobiology, chronophysiology and its subspecialities, like chronopharmacology and chronotherapy, will certainly play an important role in the clinical medicine of the future. Successful application of chronobiology to veterinary clinical medicine, however, depends critically on a... -
The effects of green tea (Camellia sinensis) flower extract on melanin synthesis in B16-F10 melanoma cells
Chanuri-Yashara Dissanayake, Hae-Hee Moon, Kyeong-Mi Yang, Younjae Lee, Chang-Hoon Han 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 8 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2018, 제 58권 제 2호 1 65-72 (8 pages)
The present study observed the effects of a green tea (Camellia sinensis) flower extract (GTFE) on melanin synthesis in B16-F10 melanoma cells. GTFE exhibited antioxidant activity on 2,2-diphenyl-1-picrylhydrazyl and inhibited mushroom tyrosinase activity in a dose-dependent manner. Furthermore, GTFE significantly diminished α-melanocyte stimulating hormone (α-MSH) stimulated cellular melanin content and tyrosinase activity throughout the concentration range evaluated. Based on RNA sequencing... -
준임상적 갑상선기능저하증
박지훈(Ji Hun Park), 김호준(Ho Jun Kim), 이명종(Myeong Jong Lee) 한방비만학회 대한한방비만학회지 13 Pages
한방비만학회 대한한방비만학회지 2006, 제 6권 제 2호 3 29-41 (13 pages)
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Sarcopenic Obesity에 대한 연구 동향 고찰
박경무(Kyung Moo Park), 송윤경(Yun Kyung Song), 임형호(Hyung Ho Lim) 한방비만학회 대한한방비만학회지 14 Pages
한방비만학회 대한한방비만학회지 2007, 제 7권 제 2호 1 1-14 (14 pages)
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음식물 불내성에 대한 고찰
박정현(Jung Hyun Park), 김호준(Ho Jun Kim), 이명종(Myeong Jong Lee) 한방비만학회 대한한방비만학회지 12 Pages
한방비만학회 대한한방비만학회지 2008, 제 8권 제 1호 1 1-12 (12 pages)
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교육연구에서 f-NIRS의 실제 측정과 적용을 통한 두뇌 연구의 탐색
박상희, 박진선, 황나래, 권승혁, 권용주 한국교원대학교 뇌기반교육연구소 Brain, Digital, & Learning 19 Pages
한국교원대학교 뇌기반교육연구소 Brain, Digital, & Learning 2019, 제 9권 제 3호 9 213-231 (19 pages)
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Antioxidant Effects of Pyrogallol in Neural Cells and Mice Brain
Jisub Moon, Heesun Gwak, Tae-Hee Lee, Eun Suk An, Yun-Bae Kim, Dongsun Park 한국교원대학교 뇌기반교육연구소 Brain, Digital, & Learning 12 Pages
한국교원대학교 뇌기반교육연구소 Brain, Digital, & Learning 2019, 제 9권 제 3호 2 113-124 (12 pages)
Polyphenols can easily react with reactive oxygen species (ROS) resulting in powerful antioxidant activity. Pyrogallol is a polyphenol found in a variety of fruits and vegetables. Therefore, plants containing pyrogallol can be used for their antioxidant, anti-bacterial, anti-fungal, anti-allergic, and anti-inflammatory properties. However, its effectiveness as an antioxidant is still a matter of debate because pyrogallol is also a superoxide anion generator and induces superoxide anion-mediated... -
Patterns of Psychosocial Adaptation to Chronic Illness and Disability
Jeong Han Kim, Norman L. Berven Yves, Ambroise Summer, Ibarra Tae Sun Kim 한국교육치료학회 교육치료연구 22 Pages
한국교육치료학회 교육치료연구 2010, Vol.2 No.2 1 1-22 (22 pages)
This study examined the patterns of psychosocial adaptation to chronic illness and disability(CID), defined in terms of subjective well-being and coping strategies in a sample of 100 individuals with various CID conditions. Cluster analysis revealed four distinct clusters of respondents, suggesting a varying degree of psychosocial adaptation. These clusters were labeled succumbing(n=9), surviving(n=40), resilient(n=41), and thriving(n=10). Our findings indicate that resilient and succumbing...
