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Potential of the Volatile-Producing Fungus Nodulisporium sp. CF016 for the Control of Postharvest Diseases of Apple
한국식물병리학회 The Plant Pathology Journal 7 Pages
한국식물병리학회 The Plant Pathology Journal 2010, 26권 3호 7 253-259 (7 pages)
In vitro and in vivo mycofumigation effects of the volatileproducing fungus Nodulisporium sp. CF016 isolated from stem of Cinnamomum loureirii and the role of its volatile compounds were investigated against phytopathogenic fungi. The volatile compounds produced by Nodulisporium sp. CF016 inhibited and killed a wide range of plant and storage pathogens including to Pythium ultimum, Rhizoctonia solani, Fusarium oxysporum, Phytophthora capsici, Sclerotinia sclerotiorum, Colletotrichum coccodes,... -
The Role of Religion in Contemporary Education
Maarten Meijer 한국종교교육학회 종교교육학연구 15 Pages
한국종교교육학회 종교교육학연구 2010, 제 34권 1 1-15 (15 pages)
Both classical philosophy and contemporary research suggest education should provide young people with opportunities to develop themselves in a well-balanced manner: Academic and intellectual advancement should take place in the context of spiritual and moral growth. This, however, is not happening in the national education system of any nation today. On the contrary, with the advancement of modern science and technology, materialism and consumerism are on the rise, and spirituality and... -
Antimicrobial Resistance and Prevalence of Plasmid- Mediated QuinoloneResistance Genes in Enrofloxacin- Resistant Avian Pathogenic Escherichia coli in Korea
Hye Jin Lee, Jin Hyun Kim, Ok Mi Jeong, Chun Tae Lim, So Youn Youn, Su jung Kim, Hee Soo Lee, Min Su Kang 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 182 310-310 (1 pages)
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Antimicrobial Resistance of E. coli isolated from Chicken during 2014-2016 in South Korea
Hye Jin Lee, Byung Kook Choi, Ok Mi Jeong, Chun Tae Lim, So Youn Youn, Byung Woo Jeon, Jun Hyeop Jeong, Su jung Kim, Hee Soo Lee, Min Su 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 181 309-310 (2 pages)
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Hematologic and serum biochemical reference intervals of the Oriental white stork (Ciconia boyciana) and the application of an automatic hematologic analyzer
Jae-Ik Han, Hye-Jin Jang, Ki-Jeong Na 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 3호 18 399-405 (7 pages)
This study was conducted to establish accurate baseline values of clinical laboratory data with regard to age-related changes in the Oriental white stork (Ciconia boyciana). In addition, the availability of an automated hematological cell counter was evaluated. A total of 94 clinically normal storks, including 64 young storks (＜1 year old; 30 male and 34 female) and 30 adults (＞ 1 year old; 17 male and 13 female) were included. Hematological assays were performed using manual and automated... -
Evaluation of effects of olfactory and auditory stimulation on separation anxiety by salivary cortisol measurement in dogs
Yoon-Joo Shin, Nam-Shik Shin* 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 2호 4 153-158 (6 pages)
Separation anxiety (SA) is a serious behavioral problem in dogs. In this study, salivary cortisol was studied to determine if the owner’s odor or voice could reduce SA in dogs. Twenty-eight dogs with SA were divided into three groups: group 1 (control), group 2 (with owner’s clothes during the separation period; SP) and group 3 (a recording of the owner’s voice was played during SP). The dog’s saliva was collected after the owner and their dog were in the experimental room for 5 min (PRE).... -
Distribution, quantitative load and characterization of Salmonella associated with swine farms in upper-northern Thailand
Pakpoom Tadee, Kittipong Kumpapong, Danai Sinthuya, Panuwat Yamsakul, Nipa Chokesajjawatee, Supachai Nuanualsuwan, Suchawan Porn 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 2호 20 327-334 (8 pages)
This study was conducted to analyze the prevalence and quantitative loads of Salmonella spp. on pig farms in Chiang Mai, Lamphun, Thailand to assess loading levels before slaughtering. The serotype diversity, antimicrobial-resistance pattern and pulse-field type of Salmonella spp. were also characterized to assess the dynamic propagation of the pathogen. The Salmonella-positive prevalence was 246/805 (30.56%), and the quantitative loads varied from 1.48∼4.04 Log10MPN/g, with a mean ± standard... -
Betulinic acid prevents alcohol-induced liver damage by improving the antioxidant system in mice
Jine Yi*, Wei Xia, Jianping Wu, Liyun Yuan, Jing Wu, Di Tu, Jun Fang, Zhuliang Tan* 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 1호 16 141-148 (8 pages)
a wide range of bioactivities. The main objective of this work was to evaluate the hepatoprotective activity of BA and the potential mechanism underlying the ability of this compound to prevent liver damage induced by alcohol in vivo. Mice were given oral doses of BA (0.25, 0.5, and 1.0 mg/kg) daily for 14 days, and induced liver injury by feeding 50% alcohol orally at the dosage of 10 ml/kg after 1 h last administration of BA. BA pretreatment significantly reduced the serum levels of alanine... -
Elm tree bark extract inhibits HepG2 hepatic cancer cell growth via pro-apoptotic activity
Tae Myoung Kim, Sang-Kyung Shin, Tae-Wang Kim, So-Young Youm, Dae Joong Kim, Byeongwoo Ahn* 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2012, 제 13권 제 1호 2 7-13 (7 pages)
chemopreventive agents. To evaluate the chemopreventive potential of BEE, we investigated the growth inhibition effect of BEE on the HepG2 human hepatocellular carcinoma cell line. We performed a cell counting kit-8 assay to determine cell viability, and 4,6-diamino-2-phenylindole staining and flow cytometry to measure apoptotic cell death. Finally, the expression levels of pro- and anti-apoptotic proteins were measured. BEE inhibited the growth of HepG2 cells and induced apoptosis in a... -
Effect of German chamomile oil application on alleviating atopic dermatitis-like immune alterations in mice
Soon-Hee Lee, Yong Heo, Young-Chul Kim, * 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2010, 제 11권 제 1호 6 35-41 (7 pages)
GC oil application for 4 weeks resulted in reduction in serum IgG1 level compared with that after 2-week application. The GC oil application group showed a significantly lower serum histamine level than the control group 2 weeks after oil application. Scratching frequency of the GC oil application group was significantly lower than either control groups. This study is to demonstrate GC oil’s immunoregulatory potential for alleviating atopic dermatitis through influencing of Th2 cell activation. -
Pyridoxine induced neuropathy by subcutaneous administration in dogs
Jin-Young Chung, Jung-Hoon Choi, Cheol-Yong Hwang, Hwa-Young Youn* 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 2호 2 127-132 (6 pages)
To construct a sensory neuropathy model, excess pyridoxine (150 mg/kg s.i.d.) was injected subcutaneously in dogs over a period of 7 days. During the administrations period, the dogs experienced body weight reduction and proprioceptive loss involving the hindquarters. After pyridoxine administration was completed, electrophysiological recordings showed that the M wave remained at a normal state, but the H-reflex of the treated dogs disappeared at 7 days. The dorsal funiculus of L4 was disrupted... -
의료용 대마(大麻)의 이해 및 법적 규제에 대한 고찰: 대마의 치료적, 학술적 필요성 제고
한경선(Kyung sun Han), 이명종(Myeong jong Lee), 김호준(Ho jun Kim) 한방비만학회 대한한방비만학회지 9 Pages
한방비만학회 대한한방비만학회지 2016, 제 16권 제 2호 7 124-132 (9 pages)
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잠재프로파일 분석을 통한 대학생의 소명과 자기실현에 따른 유형 분류 및 영향 요인 탐색
김영석, 이상희 한국교육치료학회 교육치료연구 19 Pages
한국교육치료학회 교육치료연구 2017, Vol.9 No.2 3 329-347 (19 pages)
본 연구에서는 잠재프로파일 분석을 통해 소명의 하위요인과 자기실현의 조합에 따라 잠재계층을 분류하고, 잠재계층에 따라 삶의 의미와 진로결정수준에서 차이가 나타나는지를 확인하였으며, 다항 로지스틱 회귀분석을 이용하여 잠재계층 분류에 영향을 주요인을 규명하고자 하였다. 본 연구를 통 한 주요 연구결과는 다음과 같다. 잠재프로파일 분석 결과, 4개의 계층이 도출되었으며 ‘소명 비자 기실현형’, ‘비소명형’, ‘초월부름·목적소명형’, ‘소명 자기실현형’으로 구분하여 명명하였다. 잠재계층 에 따른 삶의 의미와... -
Inhibition of voltage-dependent K+ current in rabbit coronary arterial smooth muscle cells by the class Ic antiarrhythmic drug propafenone
Jin Ryeol An, Hongliang Li, Mi Seon Seo, Won Sun Park 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.5 13 597-605 (9 pages)
In this study, we demonstrated the inhibitory effect of the Class Ic antiarrhythmic agent propafenone on voltage-dependent K+ (Kv) channels using freshly isolated coronary artery smooth muscle cells from rabbits. The Kv current amplitude was progressively inhibited by propafenone in a dose-dependent manner, with an apparent IC50 value of 5.04±1.05 μM and a Hill coefficient of 0.78±0.06. The application of propafenone had no significant effect on the steady-state activation and inactivation... -
Tricyclic antidepressant amitriptyline inhibits 5-hydroxytryptamine 3 receptor currents in NCB-20 cells
Yong Soo Park, Seok Ho Myeong, In-Beom Kim, Ki-Wug Sung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.5 12 585-595 (11 pages)
clamping experiments were reproduced by simulation and the changes of rate constants by amitriptyline were correlated with macroscopic current recording data. These results suggest that amitriptyline blocks the 5-HT3 receptor by close and open state blocking mechanisms, in a competitive manner. We could expand an understanding of pharmacological mechanisms of amitriptyline related to the modulation of a 5-HT3 receptor, a potential target of neurologic and psychiatric diseases through this study. -
Lamotrigine, an antiepileptic drug, inhibits 5-HT3 receptor currents in NCB-20 neuroblastoma cells
KiJungKim, SeungHyunJeun, Ki-WugSung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.2 4 169-177 (9 pages)
Lamotrigine is an antiepileptic drug widely used to treat epileptic seizures. Using whole-cell voltage clamp recordings in combination with a fast drug application approach, we investigated the effects of lamotrigine on 5-hydroxytryptamine (5-HT)3 receptors in NCB-20 neuroblastoma cells. Coapplication of lamotrigine (1~300 μM) resulted in a concentration-dependent reduction in peak amplitude of currents induced by 3 μM of 5-HT for an IC50 value of 28.2±3.6 μM with a Hill coefficient of... -
Gintonin facilitates catecholamine secretion from the perfused adrenal medulla
Seung-YeolNa, Ki-HwanKim, Mi-SungChoi, Kang-SuHa, Dong-YoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.6 9 629-639 (11 pages)
The present study was designed to investigate the characteristics of gintonin, one of components isolated from Korean Ginseng on secretion of catecholamines (CA) from the isolated perfused model of rat adrenal gland and to clarify its mechanism of action. Gintonin (1 to 30 μg/ml), perfused into an adrenal vein, markedly increased the CA secretion from the perfused rat adrenal medulla in a dose-dependent fashion. The gintonin-evoked CA secretion was greatly inhibited in the presence of... -
Prediction of Pharmacokinetics and Penetration of Moxifloxacin in Human with Intra-Abdominal Infection Based on Extrapolated PBPK Model
LiQinZhu, JianWeiYang, YuanZhang, YongMingWang, JianLeiZhang, YuanYuanZhao, WeiLinDong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.2 3 99-104 (6 pages)
The aim of this study is to develop a physiologically based pharmacokinetic (PBPK) model in intra- abdominal infected rats, and extrapolate it to human to predict moxifloxacin pharmacokinetics profiles in various tissues in intra-abdominal infected human. 12 male rats with intra- abdominal infections, induced by Escherichia coli, received a single dose of 40 mg/kg body weight of moxifloxacin. Blood plasma was collected at 5, 10, 20, 30, 60, 120, 240, 480, 1440 min after drug injection. A PBPK... -
A Review on Renal Toxicity Profile of Common Abusive Drugs
VarunParkashSingh, NirmalSingh, AmteshwarSinghJaggi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.4 13 347-357 (11 pages)
Drug abuse has become a major social problem of the modern world and majority of these abusive drugs or their metabolites are excreted through the kidneys and, thus, the renal complications of these drugs are very common. Morphine, heroin, cocaine, nicotine and alcohol are the most commonly abused drugs, and their use is associated with various types of renal toxicity. The renal complications include a wide range of glomerular, interstitial and vascular diseases leading to acute or chronic renal... -
Effect of Berberine on Depression- and Anxiety-Like Behaviors and Activation of the Noradrenergic System Induced by Development of Morphine Dependence in Rats
BombiLee, BongjunSur, MijungYeom, InsopShim, HyejungLee, Dae-HyunHahm 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.6 2 379-386 (8 pages)
The purpose of this study was to evaluate whether berberine (BER) administration could attenuate depression- and anxiety-like behaviors and increase corticotrophin-releasing factor (CRF) and tyrosine hydroxylase (TH) expression following chronic morphine withdrawal in rats. Male rats were exposed to chronic, intermittent, escalating morphine (10∼50 mg/kg) for 10 days. After the last morphine injection, depression- and anxiety-like beahvior associated with morphine discontinuation persisted for... -
Pretreatment of Albino Rats with Methanolic Fruit Extract of Randia Dumetorum (L.) Protects against Alcohol Induced Liver Damage
ArshadAliNoorani, MohanK.Kale 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.2 7 125-130 (6 pages)
dumetorum significantly decreased the elevated levels of ALT, AST, TG, DB, TB and lipid peroxidation compared to the group exposed to alcohol only. R. dumetorum significantly resulted in increased levels of total protein and reduced glutathione compared to the group that received alcohol only. Histology of the liver section of the animals treated with R. dumetorum improved the hepatotoxicity caused by alcohol. Hence the study concluded that R. dumetorum has potential hepatoprotective activity. -
The Protective Effect of Quercetin-3-O-β-D-Glucuronopyranoside on Ethanol-induced Damage in Cultured Feline Esophageal Epithelial Cells
JungHyunCho, SunYoungPark, HoSungLee, WanKyunnWhang, UyDongSohn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.6 1 319-326 (8 pages)
Quercetin-3-O-Ղ-D-glucuronopyranoside (QGC) is a flavonoid glucoside extracted from Rumex Aquaticus Herba. We aimed to explore its protective effect against ethanol-induced cell damage and the mechanism involved in the effect in feline esophageal epithelial cells (EEC). Cell viability was tested and 2',7'-dichlorofluorescin diacetate assay was used to detect intracellular H2O2 production. Western blotting analysis was performed to investigate MAPK activation and interleukin 6 (IL-6)... -
Modern Methods for Analysis of Antiepileptic Drugs in the Biological Fluids for Pharmacokinetics, Bioequivalence and Therapeutic Drug Monitoring
JuseopKang, Yoo-SinPark, Shin-HeeKim, Sang-HyunKim, Min-YoungJun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 16 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.2 1 67-82 (16 pages)
Epilepsy is a chronic disease occurring in approximately 1.0% of the world's population. About 30% of the epileptic patients treated with availably antiepileptic drugs (AEDs) continue to have seizures and are considered therapy-resistant or refractory patients. The ultimate goal for the use of AEDs is complete cessation of seizures without side effects. Because of a narrow therapeutic index of AEDs, a complete understanding of its clinical pharmacokinetics is essential for understanding of the... -
Maternal Social Separation of Adolescent Rats Induces Hyperactivity and Anxiolytic Behavior
HyongRyolKwak, JaeWonLee, Kwang-JunKwon, ChangDonKang, IlYoungCheong, WanjooChun, Sung-SooKim, HeeJaeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.2 2 79-84 (6 pages)
Exposure to early stressful adverse life events such as maternal and social separation plays an essential role in the development of the nervous system. Adolescent Sprague-Dawley rats that were separated on postnatal day 14 from their dam and litters (maternal social separation, MSS) showed hyperactivity and anxiolytic behavior in the open field test, elevated plus-maze test, and forced-swim test. Biologically, the number of astrocytes was significantly increased in the prefrontal cortex of MSS... -
Changes of the Level of G Protein α-subunit mRNA by Withdrawal from Morphine and Butorphanol
SeikwanOh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.4 4 291-299 (9 pages)
Morphine or butorphanol was continuously infused into cerebroventricle (i.c.v.) with the rate of 26 nmol/ μl/h for 3 days, and the withdrawal from opioid was rendered 7 hrs after the stopping of infusion. The expression of physical dependence produced by these opioids was evaluated by measuring the naloxone- precipitated withdrawal signs. The withdrawal signs produced in animals dependent on butorphanol (kappa opioid receptor agonist) were similar to those of morphine (mu opioid receptor... -
Avoidant Insecure Attachment as a Predictive Factor for Psychological Distress in Patients with Early Breast Cancer
Sang-Shin Lee, Hyo-Deog Rim, Seung-Hee Won, Jungmin Woo 대한신경정신의학회 Psychiatry Investigation 6 Pages
대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 9 805-810 (6 pages)
Objective_To identify attachment insecurity as an associative factor with unresolved psychological distress 1 year after surgery in the early breast cancer (BC) population. Methods_One-hundred fourteen participants completed the Hospital Anxiety and Depression Scale (HADS) and the Experiences in Close Relationship (ECR-M36) questionnaire within 1 week (baseline) and at 1-year post-surgery (follow-up). Participants were categorized into the distress and the non-distress groups based on a... -
The Staging of Major Mood Disorders
Ather Muneer, Rana Mazommil 대한신경정신의학회 Psychiatry Investigation 12 Pages
대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 2 747-758 (12 pages)
Objective_Staging of psychiatric disorders is gaining momentum and the purpose of this review is to examine whether major mood disorders can be defined according to stages. Methods_In April 2018 the PubMed electronic data base was scrutinized by a combination of various search terms like “major depressive disorder and staging,” “bipolar disorder and neuroprogression,” etc. To incorporate the latest findings the search was limited to the last 10 years. Both original and review articles were... -
조현병 환자를 위한 정신사회적 중재
김성완(Sung-Wan Kim) 대한신경정신의학회 신경정신의학 9 Pages
대한신경정신의학회 신경정신의학 2018, 제 57권 제 3호 5 235-243 (9 pages)
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정신증고위험군의 임상적 특성 및 진단
안석균(Suk Kyoon An) 대한신경정신의학회 신경정신의학 15 Pages
대한신경정신의학회 신경정신의학 2018, 제 57권 제 3호 2 210-224 (15 pages)
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酒精依存에서 血漿 Dopamine 및 Serotonin 濃度 變化의 意味
田珍淑, 金玹壽, 吳秉勳 대한신경정신의학회 신경정신의학 13 Pages
대한신경정신의학회 신경정신의학 1997, 제 36권 제 3호 15 547-559 (13 pages)
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정신과 입원환자의 공격행동 특성
전태연, 권용실, 도규영, 장계호 대한신경정신의학회 신경정신의학 11 Pages
대한신경정신의학회 신경정신의학 1997, 제 36권 제 3호 11 512-522 (11 pages)
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Triazolam 의존 1례 - 불안증상과 치료를 중심으로 -
박준혁, 조연규 대한신경정신의학회 신경정신의학 9 Pages
대한신경정신의학회 신경정신의학 1999, 제 38권 제 2호 19 424-432 (9 pages)
항불안제, 진정수면제로 정신과뿐만 아니라 임상각과에서 널리 사용되고 있는 벤조디아제핀(Benzodiazepine) 제재는 일정기간 이상 장기간 사용하면 내성 및 신체적, 심리적 의존이 생기고 갑자기 중단하면 금단 증상이 생기는 단점이 있어 임상의들의 각별한 주의를 요한다. 이중에서도 특히 Triazolam은 반감기가 타 벤조디아제핀 제재에 비하여 상대적으로 매우 짧아서 내성과 의존성, 그리고 금단증상이 심하다. 그럼에도 불구하고 아직 국내에는 Triazolam 의존에 대한 보고가 없다. 저자들은 Triazolam 의존에 의해 불안을 위 주로... -
Dopamine Transporter Gene의 다형성과 알코올 의존증의 관련
최윤정, 방승규, 김정진, 도규영, 백인호 대한신경정신의학회 신경정신의학 8 Pages
대한신경정신의학회 신경정신의학 1999, 제 38권 제 4호 14 826-833 (8 pages)
연구목적： 도파민계는 알코올 추구와 같은 알코올 의존증과 관련된 행동에 중요한 역할을 한다. Dopamine transporter( DAT1)는 신경연접부위에서 도파민 재흡수에 관여하여 도파민 활성을 종결시키는 물질로 알려져 있다. 그러므로, DAT1 유전자가 알코올 의존증에 대한 감수성에 영향을 줄 수 있다. DAT1 유전자는 다형 성을 보이는 반복된 40개의 염기서열(VNTR)을 갖는다. 본 연구에서는 DAT1 유전자 다형성과 알코올 의 존증 및 알코올 의존증의 임상변인과의 관련성에 대하여 알아보았다. 방 법： 알코올 의존증 환자 94명과... -
정신의학의 위기：정신과 환자, 어디로 갈 것인가?
대한신경정신의학회 신경정신의학 2000, 제 39권 제 4호 1 675-679 (5 pages)
2000년에 들어서면서 정신의학분야에는 놀라운 변화가 일어날 것이 예상된다. 이 결정적인 시점에서 우리 는 정신의학의 주체성 내지는 위기에 대해 숙고해야 한다고 본다. 다음 세기에 일어날 정신의학의 특성 및 문제상황으로는 가) 생물학적 정신의학 일변도, 나) 비정신과적 치료자 내지는 사이비 치료사들의 범람, 다) 사회의 경제적 압박으로 인한 정신과 진료의 위축 등이다. 이러한 상황적 여건은 필수적으로 다음과 같은 결과를 초래한다. 즉 가) 진료상황에서 나타낼 정신과 의사 의 안일성, 나) 피상적인 환자진료와 이에 따른... -
애착장애 아동에서 99m-Tc-ECD-SPECT로 측정한 뇌혈류량의 양상
천근아, 이경숙, 신의진 대한신경정신의학회 신경정신의학 11 Pages
대한신경정신의학회 신경정신의학 2001, 제 40권 제 1호 10 98-108 (11 pages)
연구목적： 아동 학대 또는 방치와 같은 병적인 양육환경이 신경생물학적인 변화를 야기할 수 있다는 가정 하에, 심각 한 주양육자와의 애착관계의 문제를 보이는 아동들을 대상으로 SPECT를 이용한 뇌 혈류 양상을 알아보고 뇌의 비정상 소견 여부를 관찰하고자 한다. 방 법： 연구대상은 반응성애착장애(reactive attachment disorder)로 진단된 2∼6세 아동 12명으로 구성되었다. 진단도구로서 DSM-IV, ICD-10, 낯선상황절차(Strange Situation Procedure), 사회성숙도 검사(Social Maturity Scale), 아동기 자폐증 평가척도(Childhood... -
기능성 Catechol-O-Methyltransferase 유전자 다형성과 한국인 정신분열병의 관련성
박태원, 홍영준, 박임순, 김형섭, 최인미, 배수영, 윤경식, 강대희 대한신경정신의학회 신경정신의학 10 Pages
대한신경정신의학회 신경정신의학 2001, 제 40권 제 4호 14 708-717 (10 pages)
연구목적： Catechol-O-Methyltransferase(COMT)는 카테콜아민 신경전달물질의 불활성화를 담당하는 효소로 서, 정신분열병과 관련된 후보 유전자로서 알려져 왔다. 최근, 기능성 COMT 유전자 다형성과 정신분열병 의 관련성이 제기되었는데, 한국인 정신분열병에서도 이러한 관련성이 있는지를 살피기 위해 본 연구를 시 행하였다. 방 법： 정신분열병으로 진단된 환자군 103명과 성별 및 연령별로 1：1 짝짓기 된 대조군 사이에 유전자형과 대 립유전자의 분포를 비교하였다. 또한, 환자군은 공격적 행동, 가족력, 아동기 발병 여부에... -
청소년 인터넷 중독증과 우울, 사회적 불안, 또래관계 문제와의 연관성 조사
이명수, 오은영, 조선미, 홍만제, 문재석 대한신경정신의학회 신경정신의학 11 Pages
대한신경정신의학회 신경정신의학 2001, 제 40권 제 4호 7 616-626 (11 pages)
연구목적： 본 연구는 한국 청소년들의 인터넷 사용 현황조사와 더불어 인터넷 중독증과 우울, 사회적 불안, 또래관계 문제등과의 연관성을 알아보고자 하였다. 방 법： 수원시 소재 고등학교 학생 869명(남/여＝371/498)을 대상으로 인터넷 사용과 연관된 기본 설문을 실시 하였다. 인터넷 중독여부를 알아보기 위하여 Young의 인터넷 중독척도를 사용하였고 우울증상의 평가는 Beck Depression Inventory(BDI)를 사용하였다. 사회적 불안 및 회피정도는 Social Avoidance and Distress Scale을, 부정적 평가에 대한 두려움 측정은 Fear... -
치료저항성 정신분열병 환자의 신경인지기능
이강준, 곽동일 대한신경정신의학회 신경정신의학 19 Pages
대한신경정신의학회 신경정신의학 2002, 제 41권 제 6호 8 1030-1048 (19 pages)
연구목적： 정신분열병 환자들에게서 유의한 신경인지기능장애가 존재한다는 연구결과가 많이 보고되고 있다. 본 논문은 정신분열병의 신경인지기능에 관한 좀 더 자세한 정보를 얻기 위하여 그들의 치료에 대한 반응양상을 기준으로, 임상에서 주요 문제가 되고 있는 치료저항성 정신분열병 환자군과 치료반응성 정신분열병 환자군, 정상대조군의 신경인지기능의 차이를 비교평가하여 치료저항성 정신분열병 환자 들의 특정한 신경인지기능 결함유형을 밝히고자 하였다. 이는 정신분열병의 정신병적 증상의 기저에 있는 정신병리를... -
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정신신체증상이 청소년 비행 행동에 미치는 영향
김헌수, 김현실 대한신경정신의학회 신경정신의학 9 Pages
대한신경정신의학회 신경정신의학 2003, 제 42권 제 3호 11 387-395 (9 pages)
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제주도 농촌지역 주민들의 음주습관과 우울증상 및 스트레스
대한신경정신의학회 신경정신의학 2004, 제 43권 제 1호 6 29-39 (11 pages)
