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전체 선택해제
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Effect of Ischemic Preconditioning on the Oxygen Free Radical Production in the Post-ischemic Reperfused Heart
박종완(Jong-Wan Park), 김영훈(Young-Hoon Kim), 엄창섭(Chang-Sub Uhm), 배재문(Jae-Moon Bae), 박찬웅(Chan-Woong Park), 김명석(Myung-Suk Kim) 대한약리학회 대한약리학잡지 10 Pages
대한약리학회 대한약리학잡지 1994, 제 30권 제 3호 6 321-330 (10 pages)
in detail. In an attempt to investigate the cardioprotective mechanism of PC, we examined the effects of PC on the myocardial oxidative injuries and the oxygen free radical production in the ischemia-reperfusion model of isolated Langendorff preparations of rat hearts. PC was performed with three episodes of 5 min ischemia and 5 min reperfusion before the induction of prolonged ischemia (30 min)-reperfusion(20 min). PC prevented the depression of cardiac function (left ventricular pressure x... -
Reliability and validity of a personal computer based muscle viewer for measuring upper trapezius and transverses abdominis muscle thickness
Ju-Ri Jeong, Ju Hee Han, Ji-Eun Cho, Wan-hee Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 3호 8 155-161 (7 pages)
Objective: This study aimed to investigate the reliability and validity of a personal computer-based muscle viewer (PC-BMW) compared with that of a portable ultrasound (P-US) for measuring upper trapezius (UT) and transversus abdominis (TrA) muscle thickness at rest and during contraction. Design: Observational inter-rater reliability study. Methods: Fifty-five healthy participants (25 men, 30 women) participated in this study. PC-BMW and P-US were randomly measured at the UT and TrA muscles.... -
Mechanism of UV light-induced photorelaxation in isolated rat aorta
Joo-heon Kim, Yonggeun Hong, Cheol-soo Shim 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2000, 제 1권 제 2호 4 81-86 (6 pages)
Isolated rat thoracic aorta which is pharmacologically precontracted by phenylephrine induces photorelaxation when exposed to long wave length UV-light. The aim of the present study was to characterize the mechanism of UV-light induced by photorelaxation in the rat aorta. 1. UV light relaxed both endothelium-intact and -denuded rat aortic rings contracted by phenylephrine. The magnitude of relaxation on UV light was dependent on the exposure time and slightly greatly in endothelium-denuded rings... -
Elucidation of the profound antagonism of contractile action of phenylephrine in rat aorta effected by an atypical sympathomimetic decongestant
EldinaRizvi, GoranJankovi, MiroslavM.Savi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.4 4 385-395 (11 pages)
Vasoconstrictive properties of sympathomimetic drugs are the basis of their widespread use as decongestants and possible source of adverse responses. Insufficiently substantiated practice of combining decongestants in some marketed preparations, such are those containing phenylephrine and lerimazoline, may affect the overall contractile activity, and thus their therapeutic utility. This study aimed to examine the interaction between lerimazoline and phenylephrine in isolated rat aortic rings,... -
The Inhibitory Mechanism of Gentamicin on Electrical Field Stimulation Response in Rat Bladder Smooth Muscle
ChangHoMin, YiYiWang, JinhyungBae, JungHoonHan, UyDongSohn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.5 11 473-478 (6 pages)
To see the inhibitory mechanism of gentamicin in response to electrical field stimulation (EFS) using the rat bladder smooth muscle, atropine or guanethidine was treated but had no effect. Methylsergide, a non-selective 5-HT1, 5-HT2 receptor antagonist was also treated but had on effect. Kinase inhibitors, such as chelerythrine (PKC inhibitor), ML-9 (MLCK inhibitor), or Y27632 (rho kinase inhibitor) were pretreated before gentamicin treatment, but did not have effect. For U73122, a phospholipase... -
Transient Receptor Potential C4/5 Like Channel Is Involved in Stretch-Induced Spontaneous Uterine Contraction of Pregnant Rat
SeungsooChung, Young-HwanKim, Ji-HyunJoeng, Duck-SunAhn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.6 9 503-508 (6 pages)
Spontaneous myometrial contraction (SMC) in pregnant uterus is greatly related with gestational age and growing in frequency and amplitude toward the end of gestation to initiate labor. But, an accurate mechanism has not been elucidated. In human and rat uterus, all TRPCs except TRPC2 are expressed in pregnant myometrium and among them, TRPC4 are predominant throughout gestation, suggesting a possible role in regulation of SMC. Therefore, we investigated whether the TRP channel may be involved... -
A Computational Model of Cytosolic and Mitochondrial [Ca2＋] in Paced Rat Ventricular Myocytes
JaeBoumYoum, SeongWooChoi, ChangHanJang, HyoungKyuKim, ChaeHunLeem, NariKim, JinHan 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 23 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.4 5 217-239 (23 pages)
We carried out a series of experiment demonstrating the role of mitochondria in the cytosolic and mitochondrial Ca2＋ transients and compared the results with those from computer simulation. In rat ventricular myocytes, increasing the rate of stimulation (1∼3 Hz) made both the diastolic and systolic [Ca2＋] bigger in mitochondria as well as in cytosol. As L-type Ca2＋ channel has key influence on the amplitude of Ca2＋-induced Ca2＋ release, the relation between stimulus frequency and the... -
Myoplasmic [Ca2＋], Crossbridge Phosphorylation and Latch in Rabbit Bladder Smooth Muscle
Young-DonKim, Min-HyungCho, Seong-ChunKwon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.3 8 171-177 (7 pages)
Tonic smooth muscle exhibit the latch phenomenon: high force at low myosin regulatory light chains (MRLC) phosphorylation, shortening velocity (Vo), and energy consumption. However, the kinetics of MRLC phosphorylation and cellular activation in phasic smooth muscle are unknown. The present study was to determine whether Ca2＋-stimulated MRLC phosphorylation could suffice to explain the agonist- or high K＋-induced contraction in a fast, phasic smooth muscle. We measured myoplasmic [Ca2＋], MRLC... -
Testosterone Relaxes Rabbit Seminal Vesicle by Calcium Channel Inhibition
JongKokKim, WooHaHan, MooYeolLee, SoonChulMyung, SaeChulKim, MinKyKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.2 6 73-78 (6 pages)
Recent studies have documented that testosterone relaxes several smooth muscles by modulating K+ channel activities. Smooth muscles of seminal vesicles play a fundamental role in ejaculation, which might involve testosterone. This study was aimed to assess the role of testosterone in seminal vesicular motility by studying its effects on contractile agents and on the ion channels of single vesicular myocytes in a rabbit model. The contractile responses of circular smooth muscle strips of rabbit... -
Relaxant Effect of Spermidine on Acethylcholine and High K+- induced Gastric Contractions of Guinea-Pig
YoungChulKim, JaeHoonSim, Woong-Choi, ChanHyungKim, Ra-YoungYou, Wen-XieXu, SangJinLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.2 4 59-64 (6 pages)
In our previous study, we found that spermine and putrescine inhibited spontaneous and acetylcholine (ACh)-induced contractions of guinea-pig stomach via inhibition of L-type voltage- dependent calcium current (VDCCL). In this study, we also studied the effect of spermidine on mechanical contractions and calcium channel current (IBa), and then compared its effects to those by spermine and putrescine. Spermidine inhibited spontaneous contraction of the gastric smooth muscle in a... -
Involvement of Thromboxane A2 in the Modulation of Pacemaker Activity of Interstitial Cells of Cajal of Mouse Intestine
JinHoKim, SooJinChoi, CheolHoYeum, PyungJinYoon, SeokChoi, JaeYeoulJun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.1 4 25-30 (6 pages)
membrane depolarization in current-clamp mode and increased tonic inward pacemaker currents in voltage-clamp mode. The tonic inward currents by TXA2 were inhibited by intracellular application of GDP-Ղ-S. The pretreatment of ICC with Ca2+ free solution and thapsigargin, a Ca2+-ATPase inhibitor in endoplasmic reticulum, abolished the generation of pacemaker currents and suppressed the TXA2-induced tonic inward currents. However, chelerythrine or calphostin C, protein kinase C inhibitors,... -
PGE2 Regulates Pacemaker Currents through EP2-Receptor in Cultured Interstitial Cells of Cajal from Murine Small Intestine
SeokChoi, KyungWonCho, Jong-HyunReu, Jun-SooKim, HyunSikMun, MyungYoungKim, KwangChulPark, GwangSikHeo, SungJongChang, CheolHoYeum, PyungJ 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.3 6 153-160 (8 pages)
The interstitial cells of Cajal (ICCs) are the pacemaker cells in gastrointestinal tract and generate electrical rhythmicity in gastrointestinal muscles. Therefore, ICC may be modulated by endogenous agents such as neurotransmitter, hormones, and prostaglandins (PGs). In the present study, we investigated the effects of prostaglandins, especially PGE2, on pacemaker currents in cultured ICCs from murine small intestine by using whole-cell patch clamp techniques. ICCs generated spontaneous slow... -
Cooperation of Gβ and Gαq Protein in Contractile Response of Cat Lower Esophageal Sphincter (LES)
UyDongSohnTaiSangLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.6 9 349-355 (7 pages)
We previously shown that LES contraction depends on M3 receptors linked to PTX insensitive Gq protein and activation of PLC. This results in production of IP3, which mediates calcium release, and contraction through a CaM dependent pathway. In the esophagus ACh activates M2 receptors linked to PTX sensitive Gi3 protein, resulting in activation of PLD, presumably, production of DAG. We investigated the role of PLC isozymes which can be activated by Gq or Gβ protein on ACh-induced contraction in... -
Dietary Ascorbate Supplementation Reduces Oxidative Tissue Damage and Expression of iNOS in the Kidney of Streptozotocin Induced Diabetic Rats
MyungSeoupChoi, YoonYoungJang, WooSeungLee, JinHoSong, YongKyooShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.1 8 39-45 (7 pages)
Reactive oxygen species (ROS) have been suggested to be contributory factors in complications of diabetes mellitus. In the present study, we investigated the generation of superoxide, the lipid peroxide level measured as thiobarbituric acid reactive substances, the vasorelaxation of isolated thoracic aorta and the iNOS expression in kidney of streptozotocin induced diabetic rats. Sprague Dawley rats were divided into four groups: control, ascorbate (400 mg/kg rat weight daily in drinking water),... -
Neurotensin Enhances Gastric Motility in Antral Circular Muscle Strip of Guinea-pig
TaeYongKoh, SungJoonKim, SangJinLee, TongMookKang, JaeYeoulJun, JaeHoonSim, InsukSo, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.3 7 227-234 (8 pages)
NT-induced contractile responses were abolished in Ca2-free solution and reduced greatly to near abolition by 10μM of verapamil or 0.2 mM of CdCl2. Verapamil attenuated the effects of NT on frequency and amplitude of the slow waves. Taken together, these results indicate that NT enhances contractility in guinea-pig gastric antral circular muscle and Ca2 influx through the voltage-operated Ca2 channel appears to play an important role in the NT-induced contractile mechanism. -
Decreased Voltage Dependent K+ Currents in Cerebral Arterial Smooth Muscle Cells of One-Kidney, One-Clip Goldblatt Hypertensive Rat
YoungSunOh, SeHoonKim, HoeSukKim, ByeongHwaJeon, SeokJongChang, KwangJinKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.5 3 471-479 (9 pages)
The Kv channel activity in vascular smooth muscle cell plays an important role in the regulation of membrane potential and blood vessel tone. It was postulated that increased blood vessel tone in hypertension was associated with alteration of Kv channel and membrane potential. Therefore, using whole cell mode of patch-clamp technique, the membrane potential and the 4-AP-sensitive Kv current in cerebral arterial smooth muscle cells were compared between normotensive rat and one-kidney, one-clip... -
Effect of Imipramine on Calcium Utilization of Single Cells Isolated from Canine Detrusor
Ho-ShikShim, Hyoung-ChulChoi, Young-SookJeong, Jong-HoKim, Kwang-YounLee, Uy-DongSohn, Jeoung-HeeHa, Won-JoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.4 9 439-445 (7 pages)
ACh-induced contraction was significantly inhibited by imipramine. In Ca2-free PSS, ACh-induced contraction was less than those in normal PSS and it was not affected by the pretreatment with imipramine. Ca2-induced contraction in Ca2-free PSS was supressed by imipramine, but addition of A 23187, a calcium ionophore, overcomed the inhibitory effect of imipramine. High potassium-depolarization (40 mM KCl) evoked cell contraction, which was inhibited by imipramine. Caffeine, a... -
Mechanism of Membrane Hyperpolarization by Extracellular K+ in Resistance-sized Cerebral Arterial Muscle Cell of Rabbit
SeHoonKim, KunMooChoi, HoeSukKim, ByeongHwaJeon, SeokJongChang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.1 1 1-10 (10 pages)
We sought to find out the mechanism of vascular relaxation by extracellular K concentration ([K]o) in the cerebral resistant arteriole from rabbit. Single cells were isolated from the cerebral resistant arteriole, and using voltage-clamp technique barium-sensitive K currents were recorded, and their characteristics were observed. Afterwards, the changes in membrane potential and currents through the membrane caused by the change in [K]o was observed. In the smooth... -
고양이의 담낭근 수축에 있어서 세포내 기전
임병용(Byung Yong Rhim), 김치대(Chi Dae Kim), 김동헌(Dong Heon Kim), Piero Biancani, Jose Behar 대한약리학회 대한약리학잡지 8 Pages
대한약리학회 대한약리학잡지 1996, 제 32권 제 1호 8 67-74 (8 pages)
고양이 담낭근에서 효소학적으로 분리한 평활근 세포는 cholecystokinin octapeptide (CCK-8), acetylcholine (ACh) 및 KCl에 의하여 용량에 의존하여 수축하였다. 이들 효현제 (CCK-5, ACh 및 KCl)에 의한 평활근 세포의 최대수축은 각각10-9M, 10-5M 및 20mM 농도에서 야기되었다. CCK-8에 의하여 야기되는 이들 평활근 세포의 수축은 HEPES 완충액에 Ca2+을 제거시킴에 의하여 영향을 받지 아니하였으나, Ca2+ 대신에 strontium을 첨가시켰을때 수축반응이 완전하게 억제되었다 (p<0.001). 이와는 반대로 KCl에 의한 수축반응은... -
백서의 창상치유에 미치는 연교액기스의 효과
배진우(Jin Woo Bae), 김헌준(Heon Joon Kim), 장조욱(Cho Ook Chang), 김영욱(Young Wook Kim), 조성배(Seong Bae Cho), 최재구(Jai Koo Choi) 대한약리학회 대한약리학잡지 8 Pages
대한약리학회 대한약리학잡지 1995, 제 31권 제 3호 12 377-384 (8 pages)
연교액기스가 창상치료제로서의 사용가능성을 검증하기 위하여 연교의 창상치유 효과와 독성에 대하여 조사하였으며 아울러 연교액기스가 항생작용이 있는지도 조사하였다. 연교의 창상치유 효과를 Tetrachlorodecaoxygen anion complex(TCDO) 및 단백질을 제거한 혈액투석액(Haemyl)과 생리식염수의 창상치료 효과와 비교하였다. 4일, 11일, 14일째의 창상면적은 연교액기스, TCDO, Haemyl의 치료에 의하여 대조구인 생리식염수의 치료구에 비해 유의하게 적었다. 그러나 8일째의 창상면적은 다만 연교액기스의 치료구만 유의하게... -
Sodium nitroprusside와 Forskolin의 Phorbol ester 수축에 대한 혈관이완작용의 기전
안희열(Hee Yul Ahn) 대한약리학회 대한약리학잡지 8 Pages
대한약리학회 대한약리학잡지 1995, 제 31권 제 3호 4 291-298 (8 pages)
본 연구의 목적은 protein kinase C의 활성물질인 phorbol ester의 수축에 대한 cGMP 및 cAMP의 조절기전을 명확히 하기 위하여 흰쥐의 대동맥을 재료로 실험을 수행하였다. Sodium nitroprusside는 guanylyl cyclase를 활성화시켜 cGMP를, forskolin은 adenylyl cyclase를 활성화시켜서 cAMP를 증가시키는 것으로 보고되어 있으므로 위의 두 약물을 선택하였다. Phorbol ester는 시간경과와 함께 지속적인 수축을 발생하였으며 30분경 안정상태에 도달하였다. 동시에 20-kDa myosin light chain (MLC)의 인산화도 증가하였으며 30분경... -
갑각류 골격근의 Sarcoplasmic Reticulum에서 칼슘유리
석정호(Jeong Ho Seok), 정정구(Jung Koo Jung), 허강민(Gang Min Hur), 이재흔(Jae Heun Lee) 대한약리학회 대한약리학잡지 12 Pages
대한약리학회 대한약리학잡지 1994, 제 30권 제 1호 14 125-136 (12 pages)
갑각류 골격근의 SR에서 칼슘유리 channel protein complex의 성격을 규명하기 위해 민물가재 및/또는 바다가재의 SR vesicles을 분리하여 45Ca 유리, [3H]ryanodine결합, 및 immunoblot 실험을 실시하여 다음과 같은 결과를 얻었다. 1.민물가재 SR의 [3H]ryanodine결합 실험에서 민물가재 SR의 maximal binding site및 affinity모두 바다가재에서 보다 낮았으나, high affinity binding site이었다. Extravesicles 칼슘농도를 증가시켰을 때 [3H]ryanodine결합은 약간 증가되었으나, AMP나 AMP와 caffeine을 동시에 첨가하였을 때는... -
산소유리라디칼이 뇌조직 미크로좀분획의 Na+-K+-ATPase 활성도에 미치는 영향
오세문(Sae Moon Oh)손영숙(Young Sook Son), 최길수(Kil Soo Choi), 임정규(Jung Kyoo Lim), 정명희(Myung Hee Chung) 대한약리학회 대한약리학잡지 14 Pages
대한약리학회 대한약리학잡지 1982, 제 18권 제 2호 1 1-14 (14 pages)
중추신경계의 혈관폐쇄 또는 충격손상에 의한 허혈병소에서 진행되는 병리적 변화에 산소유리라디칼이 중요한 역할을 할 것으로 시사되고 있다. 저자는 산소유리라디칼이 뇌조직에 미치는 영향 중 특히 신경세포 정지막전위 유지에 중요한 Na+-K+-ATPase의 활성도에 미치는 영향을 관찰하기 위하여 산틴산화효소 반응계와 뇌조직미크로좀을 이용하여 본 연구를 시행하였다. 미크로좀분획(microsomal fraction)을 산틴과 산틴산화효소와 함께 반응시켰을 때, 분획의 Na+-K+-ATPase의 활성도는 현저한 불활성화를 보인 반면, Mg++-ATPase의... -
부자(附子) Butanol fraction의 강심작용(强心作用)에 관한 연구(硏究)
홍사악(Hong S.A.), 박찬웅(Park C.W.), 김명석(Kim M.S.), 신상구(Shin S.G.), 대한약리학회 대한약리학잡지 8 Pages
대한약리학회 대한약리학잡지 1975, 제 11권 제 1호 1 7-14 (8 pages)
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Ca2+-activated Cl- Current in Gastric Antral Myocytes
Lee, Moo-Yeol, Bang, Hyo-Weon, Uhm, Dae-Yong, Rhee, Sang-Don 대한생리학회 대한생리학회지 8 Pages
대한생리학회 대한생리학회지 1994, 제 28권 제 2호 4 143-150 (8 pages)
The whole-cell mode of the patch clamp technique was used to study Ca2+-activated Cl- current (IClCa) in gastric antral myocytes. Extracellular application of caffeine evoked Ca2+-activated current. In order to isolate the chloride current from background current, all known systems were blocked with specific blockers. The current-voltage relationship of caffeine-induced current showed outward rectification and it reversed at around ECl-. The shift of reversal potential upon the alteration of... -
The Excitatory Mechanism of Substance P in the Antral Circular Muscle of Guinea Pig Stomach
Jun, Jae-Yeoul, Kim, Sung-Joon, Choi, Youn-Baik, Kim, Ki-Whan 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1994, 제 28권 제 1호 5 51-60 (10 pages)
This study was carried out to elucidate the excitatory mechanisms of Substance P in the antral circular muscle, using isometric contraction recording, conventional microelectrode method and whole-cell patch clamp technique. Substance P produced tonic and phasic contractions in a dose-dependent manner and depolarized membrane potential with increased amplitude of slow waves in muscle strips. Voltage-dependent Ca2+ currents were increased by the application of Substance P from a holding potential... -
Reflex Action of the Semicircular Canals on Cervical Extensor and Flexor Muscles in Cats
Kim, Jeh-Hyub, Park, Jong-Seong, 대한생리학회 대한생리학회지 8 Pages
대한생리학회 대한생리학회지 1992, 제 26권 제 2호 7 151-158 (8 pages)
In urethane anesthetized cats, each vestibular semicircular canal nerve was electrically stimulated, and reflex responses of the cervical extensor and flexor (the splenius capitis and sternomastoid muscles) were recorded by means of electromyography. Stimulation of a unilateral (anterior, horizontal or posterior) canal nerve elicited excitation of the contralateral cervical muscles and inhibition of the ipsilateral ones; during the canal nerve stimulation, the two muscles in one side of the neck... -
Effects of Cd2+ on the Contractility in the Antral Circular Muscle of Guinea-pig Stomach
Kim, Eui-Yong, Han, Jin 대한생리학회 대한생리학회지 8 Pages
대한생리학회 대한생리학회지 1992, 제 26권 제 2호 4 129-136 (8 pages)
the contracture. Cd2+ suppressed the amplitude of the Na+ tee contracture dose dependently and the amplitude of Na+ free contracture almost decreased to 20% of control amplitude in the concentration of 10-4 M Cd2+. From the above results, it is suggested that Cd2+ may inhibit not only Ca2+ influx via voltage sensitive, receptor operated Ca2+ channel and Na/ca exchange but also intracellular Ca2+ release from the sarcoplasmic reticulum in the antral circular muscle of guinea pig stomach. -
Mechanisms of Contraction Induced by Sodium Depletion in the Rabbit Renal Artery
Kim, Se-Hoon, Chang, Seok-Jong, 대한생리학회 대한생리학회지 12 Pages
대한생리학회 대한생리학회지 1991, 제 25권 제 2호 6 159-170 (12 pages)
a strain-gauge transducer. Na-free solution (Na was substituted by Li, choline or sucrose) produced contractions which were dependent on the nature of the Na substitutes. Na-free solution (choline) produced the contraction in ouabain-pretreated artery (Na loaded artery) even in the presence of verapamil. The amplitude of the contraction was dependent on the duration of the pretreatment with ouabain (105 M). Monensin potentiated the effect of ouabain on the contraction. Removal of Ca from bathing... -
Prostaglandin F2α가 가토 대동맥 평활근 수축성에 미치는 영향
정수성(Chung, Soo-Sung), 김세훈(Kim, Se-Hoon), 장석종(Chang, Seok-Jong), 박해근(Park, Hae-Kun) 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1989, 제 23권 제 1호 10 99-108 (10 pages)
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혈관 긴장도 조절에 미치는 Na-K Pump에 관한 연구
김기환(Kim, Ki-Whan), 김전(Kim, Jun) 대한생리학회 대한생리학회지 12 Pages
대한생리학회 대한생리학회지 1982, 제 16권 제 1호 1 1-12 (12 pages)
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Study on the User Selection System and the Change of Composition of Social Service Providers in Japan - Centering on the Analyses of Care Services for the Elderly andWelfare Services for Persons with Disabilities
Chang-Wan HAN, Toshihiro Fukushima, Masafumi Ide, Etsuo Horikawa 한국사회서비스학회 사회서비스연구 29 Pages
한국사회서비스학회 사회서비스연구 2011, 제 2권 제 2호 5 141-169 (29 pages)
to Contract’ and the principle of self-responsibility and to analyze the change of social service providers for the long-termcare services for the elderly andwelfare services for persons with disabilities. The biggest changes that were caused by implementing long-term care insurance are the introduction of market principle, the diversification of providers, decentralization( local transfer) and the establishment of caremanagement system. The marketization and decentralization of welfare in... -
복지관광 증진을 위한 관광사업의 전략적 발전방안
한국복지행정학회 복지행정논총 2004, 제 14권 제 2호 7 154-174 (21 pages)
본 연구는 복지관광증진을 위한 관광사업의 중요성을 강조하고자 관광사업의 범위와 시스템고찰 및 특성을 파악해보고, 관광사업의 현황 및 전망을 토대로 관광사업의 문제점 및 발전방안을 제시하였다. 본 연구의 결과를 요약하면 첫째, 복지관광 활성화방안의 하나로 공공단체 등이 위락시설을 관광소외계층 에게 무료 또는 저렴한 요금으로 이용 할 수 있는 방안을 마련하고 둘째, 재원확보를 위해 관광진흥개발기금법의 개정과 카지노업의 사업장변경 허가를 제안하였으며, 셋째, 관광호텔부가세영세율의 영구적용과... -
미성취 영재(Gifted Underachiever)에 대한 또래 상담의 전략적 개입
한국교육방법학회 교육방법연구 2002, 제 14권 제 1호 3 35-63 (29 pages)
인간의 성장과 예방을 위한 상담 활동(Growth and Prevention Model)에 대한 요구가 증가하면서 등장한 또래 상담(Peer Counseling)은 ‘비전문적인 조력자에 의한 다양한 형태의 대인 조력 활동’으로서, 비전문가에게 조력 기술을 가르쳐서 주위 또래들에게 도움을 줄 수 있게 함으로써 보다 건전하고 성숙한 또래 관계를 만들어 가도록 하는 것이다. 미성취 영재들은 잠재적인 능력에 비해 실제 성취가 그에 미치지 못하는 경우로 학습 부진 영재’하고는 달라서 자신들의 숨겨진 재능에 대한 동료들의 자극만으로도 충분한 성취를... -
개별화와 협동화 실천적 전개를 위한 통합의 논리
한국교육방법학회 교육방법연구 2005, 제 17권 제 2호 1 160-181 (22 pages)
본 연구의 일차적 목적은 개별화 학습과 협동화 학습의 이념, 배경, 특징 등을 비교해 보고, 두 대표적인 교육방법의 통합의 가능성과 통합의 형식 등을 검토해 보는 것이다. 개별화 학습이란 학습이 개별적으로 일어난다는 것에 추가해서 학습자특성에 따른 개별적인 처방이 주어진다는 점에서 교육적 기획과 배려의 뜻이 들어있다. 협동화 학습도 학습과제, 팀의 구성, 협동의 방식, 평가 등이 사전에 치밀하게 계획된 교수-학습의 형태이다. 이념과 수업의 형태가 상이하긴 하지만 두 이론의 공통점은 교수-학습에 대한 통제권 이... -
AUSTRALIAN VETERANS' AFFAIRS PAPER FOR THE INTERNATIONAL SEMINAR
Barry Telford 한국보훈학회 한국보훈학회 학술대회지 27 Pages
한국보훈학회 한국보훈학회 학술대회지 2005 국제세미나 8 280-306 (27 pages)
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정책혁신가와 학교선택제
강보길, Bogil Kang 한국교육행정학회 교육행정학연구 27 Pages
한국교육행정학회 교육행정학연구 2007, 제 25권 제 3호 3 57-83 (27 pages)
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MARKETS, STANDARDS, AND INEQUALITY
Michael W. Apple 한국교육사회학회 한국교육사회학회 학술대회자료집 52 Pages
한국교육사회학회 한국교육사회학회 학술대회자료집 2001 국제학술대회 1 1-52 (52 pages)
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Creating a new museum of ethnology in Korea is a ve까 appropriate thing to do. Over the last 50 years, Korea has become one of the most important industria1 nations of the world. Koreans have to deal with people with completely different cultural backgrounds. 1hrough migration, Korea is becoming a culturally diverse country and Koreans become global citizens. For Koreans to meet these new circurnstances it makes sense to leam how to communicate and engage with these other people effective1y. A...
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Contemporary Views of Human Resource Development
Gene Roth 한국교육학회 한국교육학회 학술대회논문집 29 Pages
한국교육학회 한국교육학회 학술대회논문집 KSSE Inter 16 365-393 (29 pages)
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A Brief Analysis on Five Elementary Components of Rousseau’s Romanticism
Wen Da, Kim Hoy-Yong 부산대학교 교육발전연구소 교육혁신연구 23 Pages
부산대학교 교육발전연구소 교육혁신연구 2016, 제 26권 제 1호 4 71-93 (23 pages)
The romantic ideology of Jean-Jacques Rousseau (1712 ~ 1778) firstly is a summary of his personal life experience, also the quintessence of his time spirit; moreover, it makes an outstanding contribution to the Enlightenment as well as the process of modernization theory. On one hand, it fills the deficiency of mainstream ideology of Enlightenment which is no longer confined to the rational and scientific knowledge; conversely, it strengthens the power of perception especially in art and... -
이주노동자 자녀의 사회권에 대한 논쟁
한국아동권리학회 아동과 권리 2009, 제 13권 제 1호 3 57-85 (29 pages)
본 연구의 목적은 우리나라의 이주노동자 자녀의 사회권 보장 현황을 파악하고 이주노동자 및 그 자녀의 사회권에 관련된 이론적 담론과 논쟁을 논의하는 것이다. 더 나아가 그 이론적 함의를 통해 사회권 보장방안을 모색하고자 하는 것이다. 본 연구는 사회권과 관련된 두 가지 이론적 시각, 즉 시민권적 접근과 인권적 접근을 통해 형성된 이주노동자 자녀의 사회권에 대한 담론을 살펴보고 그들의 사회권 보장에 있어서의 각 접근의 한계점을 알아보았다. 또한 세계화의 변화와 함께 이주노동자의 현실에 보다 더 접근한 새로운... -
금융거래계약의 관계적 특성에 관한 연구 - 고전적 계약이론과 관계적 계약이론의 비교를 중심으로 -
은행법학회 은행법연구 2015, 제 8권 제 1호 5 83-110 (28 pages)
21세기 들어 금융거래계약은 관련 파생상품의 발달과 복잡성의 증가로 인해 일반적인 소비재 거래와 비교할 수 없는 수준의 계약법적·사회적 특성을 갖기에 이르렀다. 사회적 변화와 금융의 발달과는 상관없이 고전적 계약이론의 체계에서는 금융거래계약도 당사자의 의사와 사적 자치를 중시하여 계약의 의미와 내용 및 한계를 파악해 왔다. 본 연구는 기존의 고전적 계약이론의 영향력 아래에서 금융거래계약을 파악하는 것을 지양하고 새로운 계약이론으로서 관계적 계약이론을 통해 금융거래계약의 사회적·관계적 특성을 검토하려고...
