Inhibitory effects of Cassia tora seed-derived materials against nitric oxide (NO) production were determined via evaluation of NO production. Inhibitory effects of 1,8-dihydroxyanthraquinone and 1,5-dibydroxyanthraquinone against NO production were 71.5 and 61.1% at $5;{mu}g$/mL, respectively. The suppressive effects of 1,8-dihydroxyanthraquinone completely blocked iNOS protein expression at $20;{mu}M$.