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3661.

Ethanol Elicits Inhibitory Effect on the Growth and Proliferation of Tongue Carcinoma Cells by Inducing Cell Cycle Arrest

Thanh-DoLe, ThiAnhThuDo, RinaYu, HoonYoo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.3 1 153-158 (6 pages)

Thanh-DoLe, ThiAnhThuDo, RinaYu, HoonYoo 저
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- 3,000원
Cellular effects of ethanol in YD-15 tongue carcinoma cells were assessed by MTT assay, caspase activity assay, Western blotting and flow cytometry. Ethanol inhibited the growth and proliferation of YD-15 cells in a dose- and time-dependent manner in an MTT assay. The effects of ethanol on cell cycle control at low percent range of ethanol concentration (0 to 1.5%), the condition not inducing YD-15 cell death, was investigated after exposing cells to alcohol for a certain period of time. Western...
3662.

Pretreatment of Albino Rats with Methanolic Fruit Extract of Randia Dumetorum (L.) Protects against Alcohol Induced Liver Damage

ArshadAliNoorani, MohanK.Kale 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.2 7 125-130 (6 pages)

ArshadAliNoorani, MohanK.Kale 저
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- 3,000원
Alcohol abuse and its medical and social consequences are a major health problem in many areas of the world. The present study was conducted to evaluate the protective effect of methanolic fruit extract of Randia dumetorum (L.) on alcohol-induced liver damage in rats. Rats were divided into five different groups (n=6), group I served as a control, group II received ethanol (3 ml/100 g/day p.o.), group III served as standard group and received silymarin (50 mg/kg p.o.), group IV and V served as...
3663.

Modern Methods for Analysis of Antiepileptic Drugs in the Biological Fluids for Pharmacokinetics, Bioequivalence and Therapeutic Drug Monitoring

JuseopKang, Yoo-SinPark, Shin-HeeKim, Sang-HyunKim, Min-YoungJun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 16 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.2 1 67-82 (16 pages)

JuseopKang, Yoo-SinPark, Shin-HeeKim, Sang-HyunKim, Min-YoungJun 저
...
- 4,500원
of AEDs in biological fluids is a necessity in order to explore pharmacokinetics, bioequivalence and TDM in various clinical situations. There are hundreds of published articles on the analysis of specific AEDs by a wide variety of analytical methods in biological samples have appears over the past decade. This review intends to provide an updated, concise overview on the modern method development for monitoring AEDs for pharmacokinetic studies, bioequivalence and therapeutic drug monitoring.
3664.

p38 MAPK Participates in Muscle-Specific RING Finger 1-Mediated Atrophy in Cast-Immobilized Rat Gastrocnemius Muscle

JunghwanKim, Kyung-JongWon, HwanMyungLee, Byong-YongHwang, Young-MinBae, WhanSooChoi, HyukSong, KiWonLim, Chang-KwonLee, BokyungKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.6 13 491-496 (6 pages)

JunghwanKim, Kyung-JongWon, HwanMyungLee, Byong-YongHwang, Young-MinBae, WhanSooChoi, HyukSong, KiWonLim, Chang-KwonLee, BokyungKim 저
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- 3,000원
Skeletal muscle atrophy is a common phenomenon during the prolonged muscle disuse caused by cast immobilization, extended aging states, bed rest, space flight, or other factors. However, the cellular mechanisms of the atrophic process are poorly understood. In this study, we investigated the involvement of mitogen-activated protein kinase (MAPK) in the expression of muscle-specific RING finger 1 (MuRF1) during atrophy of the rat gastrocnemius muscle. Histological analysis revealed that cast...
3665.

Janus Kinase 2 Inhibitor AG490 Inhibits the STAT3 Signaling Pathway by Suppressing Protein Translation of gp130

InAeSeo, HyunKyoungLee, YoonKyungShin, SangHwaLee, Su-YeongSeo, JiWookPark, HwanTaePark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.2 9 131-137 (7 pages)

InAeSeo, HyunKyoungLee, YoonKyungShin, SangHwaLee, Su-YeongSeo, JiWookPark, HwanTaePark 저
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- 3,000원
The binding of interleukin-6 (IL-6) cytokine family ligands to the gp130 receptor complex activates the Janus kinase (JAK)/ signal transducer and activator of transcription 3 (STAT3) signal transduction pathway, where STAT3 plays an important role in cell survival and tumorigenesis. Constitutive activation of STAT3 has been frequently observed in many cancer tissues, and thus, blocking of the gp130 signaling pathway, at the JAK level, might be a useful therapeutic approach for the suppression of...
3666.

Physiological, Pharmacological and Toxicological Implications of Heterodimeric Amino Acid Transporters

YoshikatsuKanaiHitoshiEndou 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.3 1 117-128 (12 pages)

YoshikatsuKanaiHitoshiEndou 저
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- 4,100원
may be damaging neurons leading to the exacerbation of brain damage after brain ischemia. Because of broad substrate selectivity, system L transporters such as LAT1 transport amino acid-related compounds including L-Dopa and function as a drug transporter. System L also interacts with some environmental toxins with amino acid-related structure such as cysteine-conjugated methylmercury. Therefore, these transporter would be candidates for drug targets based on new therapeutic strategies.
3667.

Electrophysiological and Morphological Classification of Inhibitory Interneurons in Layer II/III of the Rat Visual Cortex

Duck-JooRhie, HoYoungKang, GyeongRyulRyu, Myung-JunKim, ShinHeeYoon, SangJuneHahn, DoSikMin, Yang-HyeokJo, Myung-SukKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.6 5 317-323 (7 pages)

Duck-JooRhie, HoYoungKang, GyeongRyulRyu, Myung-JunKim, ShinHeeYoon, SangJuneHahn, DoSikMin, Yang-HyeokJo, Myung-SukKim 저
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- 3,000원
Interneuron diversity is one of the key factors to hinder understanding the mechanism of cortical neural network functions even with their important roles. We characterized inhibitory interneurons in layer II/III of the rat primary visual cortex, using patch-clamp recording and confocal reconstruction, and classified inhibitory interneurons into fast spiking (FS), late spiking (LS), burst spiking (BS), and regular spiking non-pyramidal (RSNP) neurons according to their electrophysiological...
3668.

단기 정신증 삽화를 보인 자기애성 인격장애 1례

조연규 대한신경정신의학회 신경정신의학 12 Pages

대한신경정신의학회 신경정신의학 1998, 제 37권 제 3호 15 562-573 (12 pages)

조연규 저
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- 4,100원
연구목적： 이 증례보고의 목적은 저자가 직접 경험한 임상례를 분석, 고찰하여 자기애성 인격장애의 임상진단 과정과 자기애성 인격장애의 하나의 증상, 증후로서의 단기 정신증 삽화의 임상적 특징 등을 알아봄으로써, 증후학 적 임상연구의 기초자료를 제시하고자 함에 있다. 방 법： DSM-Ⅳ의 진단기준에 의거하여 자기애성 인격장애로 진단받고, DSM-Ⅳ의 단기 정신병적 장애 혹은 ICD-10의 급성 및 일과성 정신병적 장애의 진단기준을 만족시키는 환자 1명을 대상으로 하였다. 환자의 임 상기록을 중심으로 자기애성 인격장애의...
3669.

비행청소년의 불안, 우울, 억압, 대처방식에 관한 연구

이재광, 진태원, 조주연 대한신경정신의학회 신경정신의학 8 Pages

대한신경정신의학회 신경정신의학 1998, 제 37권 제 3호 8 493-500 (8 pages)

이재광, 진태원, 조주연 저
...
- 3,000원
비행청소년들의 불안, 우울, 억압정도 그리고 스트레스에 대한 대처방식을 알아보기 위하여 불안척도, 우울 척도, 억압민감척도 그리고 적응척도 등을 이용하여 학생청소년 158명과 비행청소년 90명을 대상으로 본 연구를 시도하였다. 수집된 자료는 SPSS 프로그램을 이용하여 처리되었으며 자료는 변량분석에 의해서 통계처리되었다. 비행청소년들의 불안, 우울, 억압의 정도는 학생청소년들에 비해서 높았으며, 스트레스에 대한 비행청소년 들의 적응방식은 학생청소년에 비해 부적응적 적응기전을 이용하는 경향이 더 많았다....
3670.

지각된 스트레스, 역기능적 태도, 자기 효율성, 사회적 지지 및 대처양식이 물질남용 청소년의 부적응에 미치는 영향

피상순, 오상우, 박민철 대한신경정신의학회 신경정신의학 12 Pages

대한신경정신의학회 신경정신의학 2000, 제 39권 제 2호 4 297-308 (12 pages)

피상순, 오상우, 박민철 저
...
- 4,100원
연구목적： 물질남용 청소년에 대한 물질남용 교육과 치료 프로그램의 이론 설정을 위해 취약성-스트레스 모형과 사 회학습 모형 중 어느 모형이 물질남용 행동과 우울을 설명하는데 적합한 모형인가를 알아보는데 있다. 방 법： 연구대상은 물질남용을 이유로 소년원에 입소한 청소년 158명이었다. 연구도구는 반구조화된 면담 도구와 9개의 자기 보고식 질문지, 즉 지각된 스트레스, 역기능적 태도, 자기효율성, 사회적 지지, 대처양식, 물질 사 용 효과에 대한 기대, 양적 물질남용, 물질남용 관련 문제, 우울 측정 질문지였다. 자료...

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