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전체 선택해제
총 280건 검색
본문검색 결과만 보기
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Consistency of face scale choice between nursery school children and their teachers and parents while using facial expression stickers developed to improve young children's daily routines
NASU Keiko, KINJO Yasuko, ISARIDA Toshiko, NAKAMURA Mieko, OJIMA Toshiyuki 아시아아동지원학회 아시아아동지원연구 9 Pages
아시아아동지원학회 아시아아동지원연구 2012, 제 3권 3 19-27 (9 pages)
chose a fac?al expression st?cker corresponding to their evaluation of the child’s cond?tion. At home, after the even?ng meal, the children and their parents conducted daily health checks, and each chose an appropriate facial expression sticker. Consistency rates and Cohen’s Kappa were calculated by age group for school arr?val and departure, and total arrivalsl departures for all sampled children throughout the entire study period. There was moderate consistency between ch?ldren and teachers... -
The Effects of Paired Partners’ Proficiency Levels on Test-Takers’ Speaking Test Performance
Hyun IlSun 이화여자대학교 교과교육연구소 교과교육학연구 14 Pages
이화여자대학교 교과교육연구소 교과교육학연구 2017, 제 21권 2호 8 156-169 (14 pages)
of 107 female adults and college students. Based on their standardized speaking test scores, they were grouped into five levels: Superior, High, Intermediate, Novice-high, and Novice proficiency level. Then, 90 test takers completed the test three times with being paired with three different partners. The partners' proficiency levels were higher, the same as, or lower than their own. The results showed an increase in test scores, as the proficiency level of the partners is higher. Furthermore, a... -
지속적 발열 환자에서 반복 혈액배양이 유효한 균 동정률에 영향을 미치는 지에 대한 근거기반간호 사례
김나현, 최현임, 이미순, 이미경, 한다은, 김혜정, 최정순, 이미정, 박정옥, 서은정 한국근거기반간호학회 근거와 간호 4 Pages
한국근거기반간호학회 근거와 간호 2020, 제 8권 제 1호 4 31-34 (4 pages)
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임상적 징후와 정규 교환에 의한 말초정맥관 교환이 정맥염과 혈류감염 발생에 미치는 영향
윤지선, 김은옥, 서유선, 고은아, 이수열, 장주희, 김한나, 김연희 한국근거기반간호학회 근거와 간호 10 Pages
한국근거기반간호학회 근거와 간호 2016, 제 4권 제 1호 4 23-32 (10 pages)
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레이저빔을 이용한 시각적 생체 되먹임이 전방 런지운동 시 안쪽넓은근과 가쪽넓 은근의 근 활성도에 미치는 영향
공치완, 오재섭, 김미현, 안덕현, 성진욱 한국임상움직임치료학회 한국임상움직임치료학회지 8 Pages
한국임상움직임치료학회 한국임상움직임치료학회지 2021, 제 1권 제 1호 2 9-16 (8 pages)
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An investigation of factors influencing the participation of stroke survivors in social and leisure activities
Si-Nae Ahn, Su-jin Hwang 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2018, 제 7권 제 2호 4 67-71 (5 pages)
Objective: Participation restrictions are serious problems that stroke survivors experience while reintegrating into family, work, community, and social situations after participating in rehabilitation programs. The purpose of this study was to explore the factors affecting participation in activities of daily living (ADL), as well as social and leisure activities of individuals with hemiparetic stroke. Design: Cross-sectional study. Methods: The study involved 96 participants who were diagnosed... -
Reliability and validity of the patellofemoral disability index as a measure of functional performance and subjective pain in subjects with patellofemoral pain syndrome
Mastour Saeed Alshaharani, Everett Bernell Lohman, Khaled Bahjri, Travis Harp, Mansoor Alameri, Noha S. Daher 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2018, 제 7권 제 2호 3 61-66 (6 pages)
both the PDI and the ODI yielded Pearson correlation coefficient values that were positive and highly significant (range, 0.73-0.97; p<0.001). There was a high level of internal consistency (Cronbach’s α≥0.8), with the exception of stair climbing (Cronbach’s α=0.65). Intraclass correlation ranged from 0.87 to 0.92, indicating high levels of test-retest reliability. Conclusions: The PDI is a valid, reliable, and feasible method of assessing pain and functional ability in patients with PFPS. -
Construction of a new questionnaire for assessing physical therapy student attitudes towards their education and profession and testing its validity and reliability
Jaya Shanker Tedla 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2017, 제 6권 제 1호 4 20-25 (6 pages)
Objective: During the physical therapy education, if we can understand the student’s attitude then we can make valuable suggestions with respect to the teaching in the universities and professional employment in the country. The aim of the current study is to develop a questionnaire to test the physical therapy students attitudes towards their education and profession and to test its test-retest reliability and content validity. Design: Cross-sectional study. Methods: A total of 47 physical... -
Effects of ball kicking dual task training on gait performance and balance in individuals with chronic hemiparetic stroke
Min-seong Kim, Jae-hun Shim, Kyung-hoon Yu, Ji-won Kim 물리치료재활과학회 Physical Therapy Rehabilitation Science 8 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 4호 2 170-177 (8 pages)
Objective: The purpose of this study was to compare the effect of ball kicking dual task gait training with the addition of a cognitive task with general treadmill gait training (TGT) on gait speed, gait endurance, functional gait, balance and balance confidence in patients with chronic hemiparetic stroke. Design: Randomized controlled trial. Methods: Fourteen stroke patients who volunteered to participate in this study were randomly divided into two groups with seven patients in each group:... -
Wheelchair martial arts practitioners have similar bone strength, sitting balance and self-esteem to healthy individuals
Shirley S. M. Fong, Shamay S. M. Ng, Anthony O. T. Li, X. Guo 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2014, 제 3권 제 1호 5 27-32 (6 pages)
Objective: The aim of this study was to compare the radial bone strength, sitting balance ability and global self-esteem of wheelchair martial arts practitioners and healthy control participants. Design: Cross-sectional study. Methods: Nine wheelchair martial art practitioners with physical disabilities and 28 able-bodied healthy individuals participated in the study. The bone strength of the distal radius was assessed using the Sunlight Mini-Omni Ultrasound Bone Sonometer; sitting balance was... -
Effects of 3-dimensional balance trainer in combination with a video-game system on balance and gait ability in subacute stroke patients
Hyun Geun Ha, Young Jun Ko, Hwang Jae Lee, Wan Hee Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2014, 제 3권 제 1호 2 7-12 (6 pages)
Objective: The purpose of this study was to investigate the effects of a three dimensional balance trainer in combination with a video-game system and visual feedback on balance recovery and gait function in subacute stroke patients. Design: Randomized controlled trial. Methods: Twenty-three subacute stroke patients were assigned to either an experimental (n=12) or a control group (n=11) using a random permuted block design and sealed envelopes. The experimental group received additional... -
Stress and language recovery in individuals with aphasia
Brian Sharp, Paige Shaughnessy, Lee Berk, Noha Daher 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2013, 제 2권 제 2호 6 92-98 (7 pages)
of language treatment for aphasia as compared to traditional treatments. This study examined whether there are differences in cortisol stress levels between the two methods of aphasia treatment as well as effects on language skills. Design: Randomized controlled trial. Methods: A total of 20 participants with expressive aphasia were randomly placed into one of the two treatment groups. The CIAT group received 10 days of intensive treatment over two weeks. The traditional therapy group received 6... -
A Study on Assessment Design for In-class Debates - With a Focus on Case Analyses of Judging at World Debating Championships
Lee Sun Young, Park Joshua 경인교육대학교 교육연구원 The Journal of Education 20 Pages
경인교육대학교 교육연구원 The Journal of Education 2019, Vol.2 No.2 7 85-104 (20 pages)
at the highest levels of international competition, namely the World Schools Debating Championships and World Universities Debating Championship, to gain insights from the accumulated best practices from all over the world. It examines assessment standards and paradigms at WSDC/WUDC and analyzes interview data of top WSDC/WUDC judges from all over the world to access the most advanced developments in assessment methodologies and gain insights from the perspectives and experiences of expert... -
유아의 인지 과정 특성과 자유 선택 활동의 놀이 계획, 수행, 평가
유정인(Yu Jeong In) 한국교원대학교 유아교육연구소 한국유아교육연구 33 Pages
한국교원대학교 유아교육연구소 한국유아교육연구 2012, 제 14권 제 2호 5 125-157 (33 pages)
본 연구는 유아의 인지 과정 특성에 따라 자유 선택 활동의 놀이 계획, 수행, 평가의 일치 정도가 각 놀이 영역별로 어떻게 나타나며, 어떠한 관련이 있는지 알아보는 데에 목적이 있다. 본 연구의 결과 첫째, 만 5세 유아의 인지 과정 특성의 발현 정도는 106.50(SD=12.49)으로 보통인 것으로 나타났다. 인지 과정의 특성의 발현 정도는 순차처리가 가장 높았고, 계획기능, 동시처리, 주의집중의 순으로 나타났다. 둘째, 유아의 자유 선택 활동의 놀이 계획, 수행, 평가의 일치 정도는 52.57%로, 중간 정도의 일치율을 보이는 것으로... -
Hepatobiliary diseases in buffalo (Bubalus bubalis)
Arafat Khalphallah, Nasr-Eldin M. Aref, Ashraf M. Abu-Seida, Enas Elmeligy, Sara A. Bayoumi, Al-lethie A. Al-lethie, Doaa Salman 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 4호 10 543-549 (7 pages)
This study describes ultrasonographic observations of five hepatobiliary diseases in buffalo (Bubalus bubalis). Fifty buffalo, including 20 clinically normal and 30 hepatobiliary diseased buffalo were enrolled in the study. Complete clinical, radiographic and ultrasonographic examinations and laboratory analyses were conducted. Focal parenchymal lesions including liver abscess (n = 12) and hepatic cyst (n = 6), diffuse parenchymal lesion (hepatobiliary cirrhosis, n = 5) and obstruction of... -
Histopathologic findings in uteri and ovaries collected from clinically healthy dogs at elective ovariohysterectomy: a cross-sectional study
Daniel Maya-Pulgarin, Mar?a Soledad Gonzalez-Dominguez, Diego Aranzazu-Taborda, Natalia Mendoza, Juan Guillermo Maldonado-Estrad 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 3호 18 407-414 (8 pages)
Opinions on ovariohysterectomy (OHE) of bitches vary depending on region and country. In this descriptive, prospective cross-sectional study, uterine tracts and ovaries exhibiting gross pathologic findings (n = 76) were collected post-surgery from a reference population of 3,600 bitches (2.11% incidence) that underwent elective OHE during September to November 2013 and evaluated by histopathology examination. Data were evaluated by using descriptive statistics and chi-squared tests. Bitches were... -
Estrogen receptor-α, progesterone receptor, and c-erbB/HER-family receptor mRNA detection and phenotype analysis in spontaneous canine models of breast cancer
Farruk M. Lutful Kabir, Patricia DeInnocentes, Payal Agarwal, Christopher P. Mill, David J. Riese 2nd, R. Curtis Bird 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 2호 4 149-158 (10 pages)
Well characterized, stable, p16-defective canine mammary cancer (CMT) cell lines and normal canine mammary epithelial cells were used to investigate expression of the major breast cancer-specific hormone receptors estrogen receptor alpha (ER1) and progesterone receptor (PR) as well as luminal epithelial-specific proto-oncogenes encoding c-erbB-1 (epidermal growth factor receptor/EGFr), c-erbB-2/HER2, c-erbB-3, and c-erbB-4 receptors. The investigation developed and validated quantitative reverse... -
Toxicity of crude and detoxified Tityus serrulatus venom in anti-venom-producing sheep
Marina G. Ferreira, Clara G. Duarte, Maira S. Oliveira, Karen L. P. Castro, Ma?lson S. Teixeira, L?lian P. G. Reis, Jos? A. Zamb 대한수의학회 Journal of Veterinary Science 11 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 4호 5 467-477 (11 pages)
Specific anti-venom used to treat scorpion envenomation is usually obtained from horses after hyperimmunization with crude scorpion venom. However, immunized animals often become ill because of the toxic effects of the immunogens used. This study was conducted to evaluate the toxic and immunogenic activities of crude and detoxified Tityus serrulatus (Ts) venom in sheep during the production of anti-scorpionic anti-venom. Sheep were categorized into three groups: G1, control, immunized with... -
Tarantula cubensis extract alters the degree of apoptosis and mitosis in canine mammary adenocarcinomas
Nilgun Gultiken, Tolga Guvenc, Duygu Kaya, Ali Reha Agaoglu, Serhan Serhat Ay, Ibrahim Kucukaslan, Birten Emre, Murat Findik, Sa 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 2호 11 213-219 (7 pages)
In the present study, 13 clinical cases of canine mammary adenocarcinoma were evaluated in order to understand the effect of Tarantula cubensis extract (TCE) on tumor tissue. Punch biopsies were taken from the tumors before treatment with TCE. Subcutaneous injections of TCE were administered three times at weekly intervals (3 mL per dog). Between days 7 and 10 after the third injection, the tumor masses were extirpated by complete unilateral mastectomy. Pre- and post-treatment tumor tissues were... -
Canine model of ischemic stroke with permanent middle cerebral artery occlusion: clinical features, magnetic resonance imaging, histopathology, and immunohistochemistry
Joon-Hyeok Jeon, Hae-Won Jung, Hyo-Mi Jang, Jong-Hyun Moon, Ki-Tae Park, Hee-Chun Lee, Ha-Young Lim, Jung-Hyang Sur, By 대한수의학회 Journal of Veterinary Science 11 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 1호 10 75-85 (11 pages)
clinical, MRI, histopathologic, and immunohistochemical findings associated with ischemic stroke in dogs. Additionally, the association of cerebrospinal fluid (CSF) and tissue levels of interleukin (IL)-6 with clinical prognosis was assessed. Ischemic stroke was induced by permanent middle cerebral artery occlusion (MCAO) in nine healthy experimental dogs. The dogs were divided into three groups according to survival time and duration of the experimental period: group... -
Sertoli cell tumors associated with feminizing syndrome and spermatic cord torsion in two cryptorchid dogs
Marco Quartuccio, Gabriele Marino*, Giuseppe Garufi, Santo Cristarella, Antonina Zanghi 대한수의학회 Journal of Veterinary Science 3 Pages
대한수의학회 Journal of Veterinary Science 2012, 제 13권 제 2호 14 207-209 (3 pages)
a pendulous preputial sheath, prostate hypertrophy, and increased levels of circulating oestrogen. Transabdominal palpation and ultrasonography revealed the presence of neoplastic retained gonads. During surgery, spermatic cord torsion was also detected in the enlarged neoplastic testes of both dogs. Histologic examination confirmed the presence of Sertoli cell tumors that were primarily responsible for the feminizing syndrome. Complete remission of all symptoms occurred within 3 months after... -
White spots on the mucosal surface of the duodenum in dogs with lymphocytic plasmacytic enteritis
Mercedes Garc?a-Sancho, ?ngel Sainz, Alejandra Villaescusa, Antonio Rodr?guez, Fernando Rodr?guez-Franco 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2011, 제 12권 제 2호 9 165-170 (6 pages)
Distended lacteals, described as expanded white villi in duodenum, are strongly indicative of primary intestinal lymphangiectasia. In the present study, we evaluated the significance of white spots present in the duodenal mucosa of dogs with lymphocytic plasmacytic enteritis (LPE). Fifty dogs with LPE were included in this study, and white spots were detected in the duodenal mucosa in 22 dogs during endoscopy. Hypoproteinemia was more frequent in dogs with white spots than in dogs without spots... -
Functional recovery and neural differentiation after transplantation of allogenic adipose-derived stem cells in a canine model of acute spinal cord injury
Hak-Hyun Ryu, Ji-Hey Lim, Ye-Eun Byeon, Jeong-Ran Park, Min-Soo Seo, Young-Won Lee, Wan Hee Kim, Kyung-Sun Kang*, Oh-Kyeong Kweo 대한수의학회 Journal of Veterinary Science 12 Pages
대한수의학회 Journal of Veterinary Science 2009, 제 10권 제 4호 1 273-284 (12 pages)
In this study, we evaluated if the implantation of allogenic adipose-derived stem cells (ASCs) improved neurological function in a canine spinal cord injury model. Eleven adult dogs were assigned to three groups according to treatment after spinal cord injury by epidural balloon compression: C group (no ASCs treatment as control), V group (vehicle treatment with PBS), and ASC group (ASCs treatment). ASCs or vehicle were injected directly into the injured site 1 week after spinal cord injury.... -
Frequencies of Micronuclei in Peripheral Lymphocytes in Korean Populations after Chronic Low-dose Radiation Exposure
Mi-Young An and Tae-Hwan Kim 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 3호 11 213-218 (6 pages)
background levels that populations were exposed. Age and gender are the most important demographic variables in determining the MN index with frequencies in females, which were greater than those in males. The main life-style factors influencing the MN index in subjects were correlated significantly and positively with smoke. The results showed that an indicator of the genetic damaged rate in MN index in human populations significantly correlated with age, sex and life-style factors. So far, it... -
Knowledge, attitudes and practices toward antimicrobial usage: a cross-sectional study of layer and pig farm owners/managers in Chiang Mai, Lamphun, and Chonburi provinces, Thailand, May 2014 to February 2016
Aniroot Nuangmek , Suvichai Rojanasthien , Prapas Patchanee , Terdsak Yano , Panuwat Yamsakul , Suwit Chotinun , Pakpoom 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 9 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2018, 제 58권 제 1호 3 17-25 (9 pages)
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Effect of variable degrees of jejunal resection upon different clinico-biochemical parameters in dogs
Muhammad Sohail Dilawer , Muhammad Arif Khan , Zain Ul Abidin , Shahan Azeem , Khalid Abdul Majeed , Adeel Shahbaz , Aami 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 5 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2011, 제 51권 제 4호 9 309-313 (5 pages)
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백서 부분적 설절제가 하악골 성장에 미치는 영향에 관한 실험적 연구
현석환(Sug-Hwan Hyun), 김광원(Kwang-Won Kim) 대한치과교정학회 The Korean Journal of Orthodontics 9 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1995, 제 25권 제 5호 5 567-575 (9 pages)
이 연구의 목적은 부분적 설절제가 백서 하악골의 성장에 미치는 영향을 규명하기 위함이다. 생후 4주령의 옹서백서를 두 집단으로 분류하였다. 첫번째 집단은 대조군으로 사용하고 두번째 집단은 부분적으로 설절제를 시행한 집단이다. 이 실험동물은 부분적인 설절제 후 4주와 8주에 희생되었다. 부분적인 설절제 후 쥐의 하악성장변화는 건조 골표본에 의해 관찰되었다. 이 연구로부터 얻어진 결과는 다음과 같다. 1. 성장기 백서의 설절제는 하악골 자체의 형태에는 영향을 미치지 못하였으나 전반적인 하악골 성장의 감소를... -
백서 하악골의 기능적 측방편위가 하악골 성장에 미치는 영향
박관식(Kwan-Sik PARK), 경희문(Hee-Moon KYUNG), 성재현(Jae-Hyun Sung) 대한치과교정학회 The Korean Journal of Orthodontics 13 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1997, 제 27권 제 1호 9 105-117 (13 pages)
본 연구는 기능적 교합장애에 의한 하아골 측방편위가 하악골의 성장에 미치는 영향고 교합장애 제거후 나타나는 하악골의 성장양상을 알아 보기 위하여 생후 4주령의 웅성 백서의 상악우측, 하악좌측 절치를 2주 및 4주간 절단한 실험군과 4주간 절치절단을 시행하고 2주간 절단을 중지한 실험군에서 하악골계측 및 과두연골의 조직학적 변화를 관찰하여 다음과 같은 결론을 얻었다. 1. 실험 2주군에서 좌측의 하악골장경, 과두장경, 하악골고경, 과두단면적은 우측및 성장군에 비해 작은 경향을 보였고, 우측의 하악골장경,... -
비만과 건강관련 삶의 질
권영달(Young Dal Kwon) 한방비만학회 대한한방비만학회지 13 Pages
한방비만학회 대한한방비만학회지 2004, 제 4권 제 1호 11 125-137 (13 pages)
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비만치료 및 체중 감량에서 방풍통성산과 방기황기탕 사용에 대한 임상 권고안
박정현(Jung Hyun Park), 김호준(Ho Jun Kim) 한방비만학회 대한한방비만학회지 11 Pages
한방비만학회 대한한방비만학회지 2012, 제 12권 제 1호 5 48-58 (11 pages)
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Korean Music Performance Anxiety Scale: Validation and Reliability
Su-Young Bae 한국음악교육학회 음악교육연구 21 Pages
한국음악교육학회 음악교육연구 2020, 제 49권 제 3호 2 29-49 (21 pages)
of Confidence as a Speaker (PRCS) by Paul (1966). The preliminary K-MPAS comprising 26 items was conducted to 230 college music major students to verify the reliability and validity. As a result of the item analysis, it was determined that two of the 26 items were inappropriate, so the remaining 24 items were finally selected to reconstruct the K-MPAS. The scale was very high in internal consistency, split-half reliability, and test-retest reliability, and concurrent validity was also high. -
Patterns of Psychosocial Adaptation to Chronic Illness and Disability
Jeong Han Kim, Norman L. Berven Yves, Ambroise Summer, Ibarra Tae Sun Kim 한국교육치료학회 교육치료연구 22 Pages
한국교육치료학회 교육치료연구 2010, Vol.2 No.2 1 1-22 (22 pages)
This study examined the patterns of psychosocial adaptation to chronic illness and disability(CID), defined in terms of subjective well-being and coping strategies in a sample of 100 individuals with various CID conditions. Cluster analysis revealed four distinct clusters of respondents, suggesting a varying degree of psychosocial adaptation. These clusters were labeled succumbing(n=9), surviving(n=40), resilient(n=41), and thriving(n=10). Our findings indicate that resilient and succumbing... -
Tetramethylpyrazine reverses anxiety-like behaviors in a rat model of post-traumatic stress disorder
Bombi Lee, Insop Shim, Hyejung Lee, Dae-Hyun Hahm 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 14 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.5 6 525-538 (14 pages)
zone crossings in the open field test. TMP administration significantly reduced the freezing response to contextual fear conditioning and significantly restored the neurochemical abnormalities and the SPS-induced decrease in 5-HT tissue levels in the prefrontal cortex and hippocampus. The increased 5-HT concentration during TMP treatment might be partially attribute to the tryptophan and 5-hydroxyindoleacetic acid mRNA level expression in the hippocampus of rats with PTSD. These findings support... -
Effect of oleanolic acid on the activity, secretion and gene expression of matrix metalloproteinase-3 in articular chondrocytes in vitro and the production of matrix metalloproteinase-3 in vivo
Dong-GeunKang, HyunJaeLee, KunTaeKim, Sun-ChulHwang, ChoongJaeLee, JinSungPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.2 7 197-204 (8 pages)
In the present study, we tried to examine whether oleanolic acid regulates the activity, secretion and gene expression of matrix metalloproteinase-3 (MMP-3) in primary cultured rabbit articular chondrocytes, as well as the production of MMP-3 in the knee joint of rat to evaluate the potential chondroprotective effect of oleanolic acid. Rabbit articular chondrocytes were cultured in a monolayer, and reverse transcription-polymerase chain reaction (RT-PCR) was used to measure interleukin-1β... -
Participation of central GABAA receptors in the trigeminal processing of mechanical allodynia in rats
MinJiKim, YoungHongPark, KuiYeYang, JinSookJu, YongChulBae, SeongKyuHan, DongKukAhn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.1 8 65-74 (10 pages)
Here we investigated the central processing mechanisms of mechanical allodynia and found a direct excitatory link with low-threshold input to nociceptive neurons. Experiments were performed on male Sprague-Dawley rats weighing 230-280 g. Subcutaneous injection of interleukin 1 beta (IL-1β) (1 ng/10 μL) was used to produce mechanical allodynia and thermal hyperalgesia. Intracisternal administration of bicuculline, a gamma aminobutyric acid A (GABAA) receptor antagonist, produced mechanical... -
Betulin suppressed interleukin-1β-induced gene expression, secretion and proteolytic activity of matrix metalloproteinase in cultured articular chondrocytes and production of matrix metalloproteinase in the knee joint of rat
HoJongRa, HyunJaeLee, HoSeungJo, DaeCheolNam, YoungBokLee, ByeongHunKang, DongKyuMoon, DongHeeKim, ChoongJaeLee, Sun-ChulHwang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.1 3 19-26 (8 pages)
We investigated whether betulin affects the gene expression, secretion and proteolytic activity of matrix metalloproteinase-3 (MMP-3) in primary cultured rabbit articular chondrocytes, as well as in vivo production of MMP-3 in the rat knee joint to evaluate the potential chondroprotective effect of betulin. Rabbit articular chondrocytes were cultured and reverse transcription-polymerase chain reaction (RT-PCR) was used to measure interleukin-1β (IL-1β)-induced gene expression of MMP-3, MMP-1,... -
Effects of prunetin on the proteolytic activity, secretion and gene expression of MMP-3 in vitro and production of MMP-3 in vivo
DaeCheolNam, BoKunKim, , HyunJaeLee, Hyun-DaeShin, ChoongJaeLee, Sun-ChulHwang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.2 11 221-228 (8 pages)
We investigated whether prunetin affects the proteolytic activity, secretion, and gene expression of matrix metalloproteinase-3 (MMP-3) in primary cultured rabbit articular chondrocytes, as well as in vivo production of MMP-3 in the rat knee joint to evaluate the potential chondroprotective effect of prunetin. Rabbit articular chondrocytes were cultured in a monolayer, and reverse transcriptionpolymerase chain reaction (RT-PCR) was used to measure interleukin-1β (IL-1β)- induced expression of... -
Anti-inflammatory Effects of Flavonoids on TNBS-induced Colitis of Rats
MinjaeJoo, HanSangKim, TaeHoonKwon, AlishaPalikhe, TinSarZaw, JiHoonJeong, UyDongSohn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.1 7 43-50 (8 pages)
by measuring myeloperoxidase activity, nitric oxide production, tumor necrosis factor-α expression, total glutathione levels, and malondialdehyde concentrations in the colon. The results indicated that extracts including eupatilin and extracts including quercetin-3-β-D-glucuro-nopyranoside dose-dependently improved the morphology of the lesions induced by 2,4,6-trinitro-benzene sulfonic acid and reduced the ulcer index accordingly. In addition, rats receiving extracts including eupatilin and... -
Anti-Depressant Like Effect of Methyl Gallate Isolated from Acer barbinerve in Mice
Jin-KooLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.5 10 441-446 (6 pages)
in ICR mice. Body weight (BDW) and blood glucose (BDG) levels significantly decreased in the repeated restraint stress (RRS) group (2 h/day for 14 days) compared to the no stress (NS) group. To examine the effect of MG on RS-induced BDW loss and hypoglycemia, MG (10 mg/kg) and the anti-depressant fluoxetine (10 mg/kg) were administered daily for 14 days. Orally administered MG and fluoxetine significantly attenuated the RS-induced BDW loss and hypoglycemia. Interestingly, MG administered mice... -
The Role of the Pattern Edge in Goldfish Visual Motion Detection
Sun-HeeKim, Chang-SubJung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.6 10 413-417 (5 pages)
an ETR under mesopic luminance levels. For black and gray stripes, only black leading edges stimulated an ETR in all three light illumination levels. We observed less OMR and ETR results using the sine wave pattern compared to using the square wave pattern. From these results, we deduced that the goldfish tend to prefer tracking the leading edge of the pattern. The goldfish can also detect the color of the moving pattern under photopic luminance conditions. We decided that ETR is an intriguing... -
Proteomic Analysis of Differentially Expressed Proteins in Bovine Endometrium with Endometritis
ChangyongChoe, Jeong-WonPark, Eun-SukKim, Sung-GyuLee, Sun-YoungPark, Jeong-SoonLee, Myung-JeCho, KeeRyeonKang, JaeheeHan, DawonKang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.4 2 205-212 (8 pages)
semiquantitative-PCR and immunoblot analysis. The mRNA levels of desmin, transferrin, Ձ-actin-2, HSP27, KCTD11, and MHC-Ih were up-regulated by over 1.5-fold, and showed a pattern similar to their proteomic profiles. Desmin and Ձ-actin-2 protein showed positive correlations between proteomic analysis and immunoblot analysis. These results suggest that desmin and Ձ-actin-2 may play important roles in endometritis-related function, and could be useful markers for the diagnosis of... -
Involvement of Oxidative Stress and Poly(ADP-ribose) Polymerase Activation in 3-Nitropropionic Acid-induced Cytotoxicity in Human Neuroblastoma Cells
EunjooNam, YoungJaeLee, YoungAhOh, JinAhJung, HyeInIm, SeongEunKoh, SunghoMaeng, WanSeokJoo, YongSikKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.6 6 325-331 (7 pages)
3-Nitropropionic acid (3-NP) inhibits electron transport in mitochondria, leading to a metabolic failure. In order to elucidate the mechanism underlying this toxicity, we examined a few biochemical changes possibly involved in the process, such as metabolic inhibition, generation of reactive oxygen species (ROS), DNA strand breakage, and activation of Poly(ADP-ribose) polymerase (PARP). Exposure of SK-N-BE(2)C neuroblastoma cells to 3-NP for 48 h caused actual cell death, while inhibition of... -
Consistent and Specific Suppression of Mucin Release from Cultured Hamster Tracheal Surface Epithelial Cells by Poly-L-Lysine
ChoongJaeLee, JaeHeunLee, JeongHoSeok, GangMinHur, JiSunPark, SohyunBae, HyeonSeokJang, SangCheolPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.3 4 143-147 (5 pages)
during 24 h after 30 min treatment of PLL was assesed to investigate the consistency of effects. PLL did not affect the release of the other releasable glycoproteins whose molecular weights were less than mucin, and decreased the total mucin content during 24 h after 30 min treatment. We conclude that PLL can specifically suppress mucin release from cultured airway goblet cells and the suppression on mucin release is consistent. This finding suggests that PLL might be used as a specific airway... -
Combination of Electroconvulsive Therapy and Clozapine in Treatment-Resistant Schizophrenia
Jung Hyun Kim, Tak Youn, Jun Gwon Choi, Seong Hoon Jeong, Hee Yeon Jung, Yong Sik Kim, In Won Chung 대한신경정신의학회 Psychiatry Investigation 7 Pages
대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 13 829-835 (7 pages)
Objective_This study aimed to investigate the effectiveness and tolerability of the combination of electroconvulsive therapy (ECT) in patients with clozapine-treated schizophrenia. Methods_Patients with clozapine-treated schizophrenia during five years of pre-determined period were recruited from Electronic Medical Record. Clinical effects of acute ECT on psychotic symptoms were investigated. We also tried to identify predictive variables requiring maintenance treatment of ECT. Results_Fourteen... -
The Reliability and Validity of the Korean Version of the Autism-Spectrum Quotient
Ha-Young Ko, Won-Hye Lee, Eun-Kyung Won, Ji Jeong Ban, Da Eun Jung, Yeni Kim 대한신경정신의학회 Psychiatry Investigation 7 Pages
대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 6 783-789 (7 pages)
exhibited adequate internal consistency, and in most items, the HFA group scored higher in comparison to the control group. It was demonstrated that AQ has good discriminant validity through the confirmation of the significant difference in the AQ score between two groups. The concurrent validity was established through the significant correlation between AQ and EQ in the HFA group. The best estimate cut-off score of AQ for screening was 23. Conclusion_The Korean version of the AQ was determined... -
Validation of the Munich ChronoType Questionnaire in Korean Older Adults
Hyera Ryu, Eun Yeon Joo, Su Jung Choi, Sooyeon Suh 대한신경정신의학회 Psychiatry Investigation 8 Pages
대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 5 775-782 (8 pages)
Objective_This study aimed to evaluate psychometric properties of the Munich ChronoType Questionnaire (MCTQ) in a sample of Korean older adults. Methods_One-hundred ninety two participants aged 65 and over completed interview-based questionnaires about chronotype, insomnia, depression, and anxiety. Additionally, a small subset of subjects completed a 7-day sleep diary and actigraphy measurements. Results_Morningness-Eveningness Questionnaire (MEQ) scores were significantly negatively correlated...
